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Decreased Levels of GSH Are Associated with Platinum Resistance in High-Grade Serous Ovarian Cancer

High-grade serous ovarian cancer (HGSOC) is the most common and aggressive OC histotype. Although initially sensitive to standard platinum-based chemotherapy, most HGSOC patients relapse and become chemoresistant. We have previously demonstrated that platinum resistance is driven by a metabolic shif...

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Detalles Bibliográficos
Autores principales:	Criscuolo, Daniela, Avolio, Rosario, Parri, Matteo, Romano, Simona, Chiarugi, Paola, Matassa, Danilo Swann, Esposito, Franca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404763/ https://www.ncbi.nlm.nih.gov/pubmed/36009263 http://dx.doi.org/10.3390/antiox11081544

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