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Transcriptional Regulator DasR Represses Daptomycin Production through Both Direct and Cascade Mechanisms in Streptomyces roseosporus

Daptomycin, produced by Streptomyces roseosporus, is a clinically important cyclic lipopeptide antibiotic used for the treatment of human infections caused by drug-resistant Gram-positive pathogens. In contrast to most Streptomyces antibiotic biosynthetic gene clusters (BGCs), daptomycin BGC has no...

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Detalles Bibliográficos
Autores principales:	Chen, Qiong, Zhu, Jianya, Li, Xingwang, Wen, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404778/ https://www.ncbi.nlm.nih.gov/pubmed/36009934 http://dx.doi.org/10.3390/antibiotics11081065

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