Cargando…

Synthesis and Antioxidant Properties of HeteroBisNitrones Derived from Benzene Dicarbaldehydes

We report herein the synthesis and antioxidant profile of nine novel heterobisnitrones (hBNs) as new α-phenyl-tert-butylnitrone (PBN) analogues. The synthesized hBNs 1–9 were evaluated for their antioxidant activity using different in vitro techniques, while they were also tested as inhibitors of so...

Descripción completa

Detalles Bibliográficos
Autores principales:	Diez-Iriepa, Daniel, Iriepa, Isabel, López-Muñoz, Francisco, Marco-Contelles, José, Hadjipavlou-Litina, Dimitra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404792/ https://www.ncbi.nlm.nih.gov/pubmed/36009295 http://dx.doi.org/10.3390/antiox11081575

Ejemplares similares

Homo-Tris-Nitrones Derived from α-Phenyl-N-tert-butylnitrone: Synthesis, Neuroprotection and Antioxidant Properties
por: Diez-Iriepa, Daniel, et al.
Publicado: (2020)

Polyfunctionalized α-Phenyl-tert-butyl(benzyl)nitrones: Multifunctional Antioxidants for Stroke Treatment
por: Diez-Iriepa, Daniel, et al.
Publicado: (2022)

Synthesis, antioxidant properties and neuroprotection of α-phenyl-tert-butylnitrone derived HomoBisNitrones in in vitro and in vivo ischemia models
por: Chamorro, Beatriz, et al.
Publicado: (2020)

Synthesis and Antioxidant Properties of Novel 1,2,3-Triazole-Containing Nitrones
por: Hadjipavlou-Litina, Dimitra, et al.
Publicado: (2022)

Nucleobase-Derived Nitrones: Synthesis and Antioxidant and Neuroprotective Activities in an In Vitro Model of Ischemia–Reperfusion
por: Chamorro, Beatriz, et al.
Publicado: (2022)

Synthesis and Neuroprotective Properties of N-Substituted C-Dialkoxyphosphorylated Nitrones
por: Piotrowska, Dorota G., et al.
Publicado: (2019)

Synthesis, Neuroprotection, and Antioxidant Activity of 1,1′-Biphenylnitrones as α-Phenyl-N-tert-butylnitrone Analogues in In Vitro Ischemia Models
por: Chamorro, Beatriz, et al.
Publicado: (2021)

5-Chloro-2-hydroxybenzene-1,3-dicarbaldehyde
por: Jiang, Jue-Chao, et al.
Publicado: (2008)

Triazolopyridopyrimidine: A New Scaffold for Dual-Target Small Molecules for Alzheimer’s Disease Therapy
por: Zribi, Lazhar, et al.
Publicado: (2020)

Neuroprotective and Antioxidant Properties of CholesteroNitrone ChN2 and QuinolylNitrone QN23 in an Experimental Model of Cerebral Ischemia: Involvement of Necrotic and Apoptotic Cell Death
por: Chamorro, Beatriz, et al.
Publicado: (2023)

Melatonin and Nitrones As Potential Therapeutic Agents for Stroke
por: Romero, Alejandro, et al.
Publicado: (2016)

Novel Cinnamic Acid Derivatives as Antioxidant and Anticancer Agents: Design, Synthesis and Modeling Studies
por: Pontiki, Eleni, et al.
Publicado: (2014)

Corrigendum: Melatonin and Nitrones As Potential Therapeutic Agents for Stroke
por: Romero, Alejandro, et al.
Publicado: (2017)

Synthesis of Hantzsch Adducts as Cholinesterases and Calcium Flux inhibitors, Antioxidants and Neuroprotectives
por: Pachón Angona, Irene, et al.
Publicado: (2020)

Privileged Quinolylnitrones for the Combined Therapy of Ischemic Stroke and Alzheimer’s Disease
por: Alonso, José M., et al.
Publicado: (2021)

Neuroprotective and antioxidant properties of new quinolylnitrones in in vitro and in vivo cerebral ischemia models
por: Chamorro, Beatriz, et al.
Publicado: (2023)

Multi-Target Cinnamic Acids for Oxidative Stress and Inflammation: Design, Synthesis, Biological Evaluation and Modeling Studies
por: Pontiki, Eleni, et al.
Publicado: (2018)

QuinoxalineTacrine QT78, a Cholinesterase Inhibitor as a Potential Ligand for Alzheimer’s Disease Therapy
por: Ramos, Eva, et al.
Publicado: (2019)

2-Arylidene-1-indandiones as Pleiotropic Agents with Antioxidant and Inhibitory Enzymes Activities †
por: Kouzi, Olympia, et al.
Publicado: (2019)

Donepezil + chromone + melatonin hybrids as promising agents for Alzheimer’s disease therapy
por: Pachón-Angona, Irene, et al.
Publicado: (2019)

Synthesis and Pharmacochemistry of New Pleiotropic Pyrrolyl Derivatives
por: Konstantinidou, Markella, et al.
Publicado: (2015)

Crystal structure of 3,6-dihydroxy-4,5-dimethylbenzene-1,2-dicarbaldehyde
por: Yamazaki, Shu, et al.
Publicado: (2018)

Amidinoquinoxaline-Based Nitrones as Lipophilic Antioxidants
por: Gruber, Nadia, et al.
Publicado: (2021)

Imidazopyranotacrines as Non-Hepatotoxic, Selective Acetylcholinesterase Inhibitors, and Antioxidant Agents for Alzheimer′s Disease Therapy
por: Boulebd, Houssem, et al.
Publicado: (2016)

Straightforward Synthesis of Bis[(trifluoromethyl)sulfonyl]ethylated Isocoumarins from 2-Ethynylbenzoates
por: Petcu, A. Sonia, et al.
Publicado: (2023)

The Occurrence of Flavonoids and Related Compounds in Cedrus brevifolia A. Henry ex Elwes & A. Henry Needles. Inhibitory Potencies on Lipoxygenase, Linoleic Acid Lipid Peroxidation and Antioxidant Activity
por: Douros, Andreas, et al.
Publicado: (2017)

Crystal structures of methyl 3,5-dimethylbenzoate, 3,5-bis(bromomethyl)phenyl acetate and 5-hydroxybenzene-1,3-dicarbaldehyde
por: Ebersbach, Ben, et al.
Publicado: (2022)

Preclinical Characterization of Antioxidant Quinolyl Nitrone QN23 as a New Candidate for the Treatment of Ischemic Stroke
por: Martínez-Alonso, Emma, et al.
Publicado: (2022)

Curcumin in Health and Diseases: Alzheimer’s Disease and Curcumin Analogues, Derivatives, and Hybrids
por: Chainoglou, Eirini, et al.
Publicado: (2020)

The novel amidocarbamate derivatives of ketoprofen: synthesis and biological activity
por: Rajić, Zrinka, et al.
Publicado: (2010)

9-Allyl-9H-carbazole-3,6-dicarbaldehyde
por: Hu, Bin Bin, et al.
Publicado: (2012)

N-Hydroxy-N-Propargylamide Derivatives of Ferulic Acid: Inhibitors of Cholinesterases and Monoamine Oxidases
por: Bautista-Aguilera, Óscar M., et al.
Publicado: (2022)

Synthesis, Antimicrobial, and Antioxidant Activities of Chalcogen-Containing Nitrone Derivatives from (R)-citronellal
por: Ferraz, Mariana C., et al.
Publicado: (2017)

Hybrids as NO Donors
por: Tsopka, Ioanna-Chrysoula, et al.
Publicado: (2021)

2,2′-Dihydroxybiphenyl-3,3′-dicarbaldehyde dioxime
por: Golovnia, Ekaterina, et al.
Publicado: (2009)

Multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer’s disease: design, synthesis, biochemical evaluation, ADMET, molecular modeling, and QSAR analysis of novel donepezil-pyridyl hybrids
por: Bautista-Aguilera, Oscar M, et al.
Publicado: (2014)

Use of Radical Oxygen Species Scavenger Nitrones to Treat Oxidative Stress-Mediated Hearing Loss: State of the Art and Challenges
por: Varela-Nieto, Isabel, et al.
Publicado: (2021)

Pyrazoles and Pyrazolines as Anti-Inflammatory Agents
por: Mantzanidou, Martha, et al.
Publicado: (2021)

2,3,5,6-Tetramethoxypiperazine-1,4-dicarbaldehyde
por: Moosavi, Sayed Mojtaba, et al.
Publicado: (2009)

Boronic Acid Group: A Cumbersome False Negative Case in the Process of Drug Design
por: Katsamakas, Sotirios, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_43tbj5i1544qauior3kqm9uunj