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Mutant Huntingtin Derails Cysteine Metabolism in Huntington’s Disease at Both Transcriptional and Post-Translational Levels

Cysteine is a semi-essential amino acid that not only plays an essential role as a component of protein synthesis, but also in the generation of numerous sulfur-containing molecules such as the antioxidant glutathione and coenzyme A. We previously showed that the metabolism of cysteine is dysregulat...

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Detalles Bibliográficos
Autores principales:	Paul, Bindu D., Sbodio, Juan I., Snyder, Solomon H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404835/ https://www.ncbi.nlm.nih.gov/pubmed/36009188 http://dx.doi.org/10.3390/antiox11081470

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