A Brominated Furanone Inhibits Pseudomonas aeruginosa Quorum Sensing and Type III Secretion, Attenuating Its Virulence in a Murine Cutaneous Abscess Model

Quorum sensing (QS) and type III secretion systems (T3SSs) are among the most attractive anti-virulence targets for combating multidrug-resistant pathogenic bacteria. Some halogenated furanones reduce QS-associated virulence, but their role in T3SS inhibition remains unclear. This study aimed to ass...

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Detalles Bibliográficos
Autores principales: Muñoz-Cázares, Naybi, Castillo-Juárez, Israel, García-Contreras, Rodolfo, Castro-Torres, Víctor Alberto, Díaz-Guerrero, Miguel, Rodríguez-Zavala, José S., Quezada, Héctor, González-Pedrajo, Bertha, Martínez-Vázquez, Mariano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404868/
https://www.ncbi.nlm.nih.gov/pubmed/36009394
http://dx.doi.org/10.3390/biomedicines10081847

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