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Genetic and Pharmacological Inhibition of GCN2 Ameliorates Hyperglycemia and Insulin Resistance in Type 2 Diabetic Mice

It is well recognized that there is a strong and complex association between nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes (T2D). We previously demonstrated that genetic knockout or pharmacological inhibition of general control nondepressible kinase 2 (GCN2), a well-known amino acid s...

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Detalles Bibliográficos
Autores principales: Yuan, Juntao, Li, Fang, Shen, Xiyue, Gao, Junling, Yu, Zhuoran, Luo, Kai, Cui, Bingqing, Lu, Zhongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404927/
https://www.ncbi.nlm.nih.gov/pubmed/36009303
http://dx.doi.org/10.3390/antiox11081584

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