Cargando…

Gene Ontology Analysis Highlights Biological Processes Influencing Non-Response to Anti-TNF Therapy in Rheumatoid Arthritis

Anti-TNF therapy has significantly improved disease control in rheumatoid arthritis, but a fraction of rheumatoid arthritis patients do not respond to anti-TNF therapy or lose response over time. Moreover, the mechanisms underlying non-response to anti-TNF therapy remain largely unknown. To date, ma...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jezernik, Gregor, Gorenjak, Mario, Potočnik, Uroš
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404936/ https://www.ncbi.nlm.nih.gov/pubmed/36009355 http://dx.doi.org/10.3390/biomedicines10081808

Ejemplares similares

Gene Ontology Analysis Highlights Biological Processes Influencing Responsiveness to Biological Therapy in Psoriasis
por: Krušič, Martina, et al.
Publicado: (2023)

MIF Variant rs755622 Is Associated with Severe Crohn’s Disease and Better Response to Anti-TNF Adalimumab Therapy
por: Jezernik, Gregor, et al.
Publicado: (2023)

Omics data integration identifies ELOVL7 and MMD gene regions as novel loci for adalimumab response in patients with Crohn’s disease
por: Gorenjak, Mario, et al.
Publicado: (2021)

Identification of Novel Loci Involved in Adalimumab Response in Crohn’s Disease Patients Using Integration of Genome Profiling and Isoform-Level Immune-Cell Deconvoluted Transcriptome Profiling of Colon Tissue
por: Gorenjak, Mario, et al.
Publicado: (2022)

Meta-Analytic Comparison of Global RNA Transcriptomes of Acute and Chronic Myeloid Leukemia Cells Reveals Novel Gene Candidates Governing Myeloid Malignancies
por: Jurgec, Staša, et al.
Publicado: (2022)

MFUM-BrTNBC-1, a Newly Established Patient-Derived Triple-Negative Breast Cancer Cell Line: Molecular Characterisation, Genetic Stability, and Comprehensive Comparison with Commercial Breast Cancer Cell Lines
por: Skok, Kristijan, et al.
Publicado: (2021)

Molecular Genetic Architecture of Monogenic Pediatric IBD Differs from Complex Pediatric and Adult IBD
por: Jezernik, Gregor, et al.
Publicado: (2020)

Dysregulation of Synaptic Signaling Genes Is Involved in Biology of Uterine Leiomyoma
por: Krsteski, Jovan, et al.
Publicado: (2021)

Pre-Treatment Biomarkers of Anti-Tumour Necrosis Factor Therapy Response in Crohn’s Disease—A Systematic Review and Gene Ontology Analysis
por: Gole, Boris, et al.
Publicado: (2019)

The Effect of TNF and Non-TNF-Targeted Biologics on Body Composition in Rheumatoid Arthritis
por: Vial, Gaelle, et al.
Publicado: (2021)

Influence of anti-TNF therapy on monocyte gene expression in rheumatoid arthritis
por: Hernandez, M, et al.
Publicado: (2003)

De novo mutation in KITLG gene causes a variant of Familial Progressive Hyper‐ and Hypo‐pigmentation (FPHH)
por: Gorenjak, Mario, et al.
Publicado: (2021)

Cholecalciferol Supplementation Induced Up-Regulation of SARAF Gene and Down-Regulated miR-155-5p Expression in Slovenian Patients with Multiple Sclerosis
por: Gselman, Saša, et al.
Publicado: (2023)

Transcriptomics of receptive endometrium in women with sonographic features of adenomyosis
por: Prašnikar, Erika, et al.
Publicado: (2022)

An orally available small molecule that targets soluble TNF to deliver anti-TNF biologic-like efficacy in rheumatoid arthritis
por: Vugler, Alexander, et al.
Publicado: (2022)

Clinical and functional effectiveness of anti-TNF therapy in patients with rheumatoid arthritis
por: Martínez-Pérez, Rosalia, et al.
Publicado: (2011)

Risk of Tuberculosis Reactivation in Patients with Rheumatoid Arthritis, Ankylosing Spondylitis, and Psoriatic Arthritis Receiving Non-Anti-TNF-Targeted Biologics
por: Cantini, Fabrizio, et al.
Publicado: (2017)

Biological Anti-TNF-α Therapy and Markers of Oxidative and Carbonyl Stress in Patients with Rheumatoid Arthritis
por: Šteňová, Emőke, et al.
Publicado: (2021)

Discontinuation rates of biologics in patients with rheumatoid arthritis: are TNF inhibitors different from non-TNF inhibitors?
por: Ramiro, Sofia, et al.
Publicado: (2015)

Anti-TNF-α effects on anemia in rheumatoid and psoriatic arthritis
por: Corrado, Addolorata, et al.
Publicado: (2017)

Metabolic Effects of Anti-TNF-α Treatment in Rheumatoid Arthritis
por: Macáková, Kristína, et al.
Publicado: (2023)

Blood-based identification of non-responders to anti-TNF therapy in rheumatoid arthritis
por: Thomson, Ty M., et al.
Publicado: (2015)

Efficacy and Safety of Rituximab in Biologic-Naive Patients with Rheumatoid Arthritis vs Anti-Tnf Therapy Failure
por: Gutierrez-Gonzalez, Luis Arturo, et al.
Publicado: (2013)

Structural Biology of the TNFα Antagonists Used in the Treatment of Rheumatoid Arthritis
por: Lim, Heejin, et al.
Publicado: (2018)

Hepatorenal pathologies in TNF-transgenic mouse model of rheumatoid arthritis are alleviated by anti-TNF treatment
por: Li, Xuefei, et al.
Publicado: (2023)

Economic evaluation of anti-TNF agents for patients with rheumatoid arthritis in Greece
por: Fragoulakis, Vasilis, et al.
Publicado: (2015)

Disease Differentiation and Monitoring of Anti-TNF Treatment in Rheumatoid Arthritis and Spondyloarthropathies
por: Bogunia-Kubik, Katarzyna, et al.
Publicado: (2021)

Influence of NKG2D Genetic Variants on Response to Anti-TNF Agents in Patients with Rheumatoid Arthritis
por: Iwaszko, Milena, et al.
Publicado: (2018)

Anti-TNF drives regulatory T cell expansion by paradoxically promoting membrane TNF–TNF-RII binding in rheumatoid arthritis
por: Nguyen, Dao Xuan, et al.
Publicado: (2016)

Risk of septic arthritis in patients with rheumatoid arthritis and the effect of anti-TNF therapy: results from the British Society for Rheumatology Biologics Register
por: Galloway, J B, et al.
Publicado: (2011)

Ultrasound Detection of Salmonella Septic Arthritis in a Rheumatoid Arthritis Patient on Anti-TNF Treatment
por: Nandagudi, Anupama C., et al.
Publicado: (2014)

Influence of Insulin Resistance and TNF-α on the Inflammatory Process, Oxidative Stress, and Disease Activity in Patients with Rheumatoid Arthritis
por: Costa, Neide Tomimura, et al.
Publicado: (2016)

Influence of anti-TNF therapy on mortality in patients with rheumatoid arthritis-associated interstitial lung disease: results from the British Society for Rheumatology Biologics Register
por: Dixon, W G, et al.
Publicado: (2010)

Benefit of anti-TNF therapy in rheumatoid arthritis patients with moderate disease activity
por: Hyrich, Kimme L., et al.
Publicado: (2009)

Do anti-TNF agents have equal efficacy in patients with rheumatoid arthritis?
por: Schwartzman, Sergio, et al.
Publicado: (2004)

Paradoxical psoriasis after the use of anti-TNF in a patient with rheumatoid arthritis
por: de Vasconcellos, Jaqueline Barbeito, et al.
Publicado: (2016)

The Effect of Anti-TNF Therapy on Cardiac Function in Rheumatoid Arthritis: An Observational Study
por: Baniaamam, Milad, et al.
Publicado: (2020)

Demyelinating Events Following Initiation of Anti-TNFα Therapy in the British Society for Rheumatology Biologics Registry in Rheumatoid Arthritis
por: Taylor, Thomas R.P., et al.
Publicado: (2021)

The Influence of Severity and Disease Duration on TNF Receptors’ Redistribution in Asthma and Rheumatoid Arthritis
por: Alshevskaya, Alina, et al.
Publicado: (2022)

Bone and TNF in rheumatoid arthritis: clinical implications
por: Manara, Maria, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_9va7motmk88gagmkaivefjriai