T-Cell Infiltration and Immune Checkpoint Expression Increase in Oral Cavity Premalignant and Malignant Disorders

The immune cell niche associated with oral dysplastic lesion progression to carcinoma is poorly understood. We identified T regulatory cells (Treg), CD8(+) effector T cells (Teff) and immune checkpoint molecules across oral dysplastic stages of oral potentially malignant disorders (OPMD). OPMD and o...

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Detalles Bibliográficos
Autores principales: Surendran, Subin, Aboelkheir, Usama, Tu, Andrew A., Magner, William J., Sigurdson, S. Lynn, Merzianu, Mihai, Hicks, Wesley L., Suresh, Amritha, Kirkwood, Keith L., Kuriakose, Moni A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404942/
https://www.ncbi.nlm.nih.gov/pubmed/36009387
http://dx.doi.org/10.3390/biomedicines10081840

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