Model-Informed Translation of In Vitro Effects of Short-, Prolonged- and Continuous-Infusion Meropenem against Pseudomonas aeruginosa to Clinical Settings

Pharmacokinetic-pharmacodynamic (PKPD) models have met increasing interest as tools to identify potential efficacious antibiotic dosing regimens in vitro and in vivo. We sought to investigate the impact of diversely shaped clinical pharmacokinetic profiles of meropenem on the growth/killing patterns...

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Detalles Bibliográficos
Autores principales: Minichmayr, Iris K., Kappetein, Suzanne, Brill, Margreke J. E., Friberg, Lena E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404958/
https://www.ncbi.nlm.nih.gov/pubmed/36009905
http://dx.doi.org/10.3390/antibiotics11081036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404958/
https://www.ncbi.nlm.nih.gov/pubmed/36009905
http://dx.doi.org/10.3390/antibiotics11081036

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