Antioxidant Therapy Significantly Attenuates Hepatotoxicity following Low Dose Exposure to Microcystin-LR in a Murine Model of Diet-Induced Non-Alcoholic Fatty Liver Disease

We have previously shown in a murine model of Non-alcoholic Fatty Liver Disease (NAFLD) that chronic, low-dose exposure to the Harmful Algal Bloom cyanotoxin microcystin-LR (MC-LR), resulted in significant hepatotoxicity including micro-vesicular lipid accumulation, impaired toxin metabolism as well...

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Detalles Bibliográficos
Autores principales: Lad, Apurva, Hunyadi, Jonathan, Connolly, Jacob, Breidenbach, Joshua D., Khalaf, Fatimah K., Dube, Prabhatchandra, Zhang, Shungang, Kleinhenz, Andrew L., Baliu-Rodriguez, David, Isailovic, Dragan, Hinds, Terry D., Gatto-Weis, Cara, Stanoszek, Lauren M., Blomquist, Thomas M., Malhotra, Deepak, Haller, Steven T., Kennedy, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9404967/
https://www.ncbi.nlm.nih.gov/pubmed/36009344
http://dx.doi.org/10.3390/antiox11081625

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