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End-to-end pipeline for differential analysis of pausing in ribosome profiling data

Ribosome profiling is a powerful technique which maps the distribution of ribosomes along mRNAs to analyze translation genome-wide. Ribosome density can be affected by multiple factors, such as changes to translation initiation or elongation rates. We describe the application of a metric for identif...

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Detalles Bibliográficos
Autores principales: Flanagan, Keegan, Li, Wanxin, Greenblatt, Ethan J., Dao Duc, Khanh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405084/
https://www.ncbi.nlm.nih.gov/pubmed/36035799
http://dx.doi.org/10.1016/j.xpro.2022.101605