Improved treatment robustness of postoperative breast cancer radiotherapy including supraclavicular nodes

A combination of a three-dimensional conformal radiation therapy (3D-CRT) plan with a dose gradient of the chest wall area and a volumetric modulated arc therapy (VMAT) plan of the supraclavicular area might improve the dose distribution robustness in the junction. To investigate the impact of patie...

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Detalles Bibliográficos
Autores principales: Miura, Hideharu, Doi, Yoshiko, Nakao, Minoru, Ozawa, Shuichi, Kenjo, Masahiro, Nagata, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Technical Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405093/
https://www.ncbi.nlm.nih.gov/pubmed/36035090
http://dx.doi.org/10.1016/j.phro.2022.08.004
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author Miura, Hideharu
Doi, Yoshiko
Nakao, Minoru
Ozawa, Shuichi
Kenjo, Masahiro
Nagata, Yasushi
author_facet Miura, Hideharu
Doi, Yoshiko
Nakao, Minoru
Ozawa, Shuichi
Kenjo, Masahiro
Nagata, Yasushi
author_sort Miura, Hideharu
collection PubMed
description A combination of a three-dimensional conformal radiation therapy (3D-CRT) plan with a dose gradient of the chest wall area and a volumetric modulated arc therapy (VMAT) plan of the supraclavicular area might improve the dose distribution robustness in the junction. To investigate the impact of patient motion on the dose distribution, hybrid 3D-CRT and VMAT plans were recalculated by shifting the isocenter of the VMAT plan. Compared to the nominal plan, the target D(98%) for high- vs low-dose gradients decreased by 24% vs 12%. Hybrid VMAT with a low-dose gradient 3D-CRT plan was found to be robust towards patient motion.
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spelling pubmed-94050932022-08-26 Improved treatment robustness of postoperative breast cancer radiotherapy including supraclavicular nodes Miura, Hideharu Doi, Yoshiko Nakao, Minoru Ozawa, Shuichi Kenjo, Masahiro Nagata, Yasushi Phys Imaging Radiat Oncol Technical Note A combination of a three-dimensional conformal radiation therapy (3D-CRT) plan with a dose gradient of the chest wall area and a volumetric modulated arc therapy (VMAT) plan of the supraclavicular area might improve the dose distribution robustness in the junction. To investigate the impact of patient motion on the dose distribution, hybrid 3D-CRT and VMAT plans were recalculated by shifting the isocenter of the VMAT plan. Compared to the nominal plan, the target D(98%) for high- vs low-dose gradients decreased by 24% vs 12%. Hybrid VMAT with a low-dose gradient 3D-CRT plan was found to be robust towards patient motion. Elsevier 2022-08-13 /pmc/articles/PMC9405093/ /pubmed/36035090 http://dx.doi.org/10.1016/j.phro.2022.08.004 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Technical Note
Miura, Hideharu
Doi, Yoshiko
Nakao, Minoru
Ozawa, Shuichi
Kenjo, Masahiro
Nagata, Yasushi
Improved treatment robustness of postoperative breast cancer radiotherapy including supraclavicular nodes
title Improved treatment robustness of postoperative breast cancer radiotherapy including supraclavicular nodes
title_full Improved treatment robustness of postoperative breast cancer radiotherapy including supraclavicular nodes
title_fullStr Improved treatment robustness of postoperative breast cancer radiotherapy including supraclavicular nodes
title_full_unstemmed Improved treatment robustness of postoperative breast cancer radiotherapy including supraclavicular nodes
title_short Improved treatment robustness of postoperative breast cancer radiotherapy including supraclavicular nodes
title_sort improved treatment robustness of postoperative breast cancer radiotherapy including supraclavicular nodes
topic Technical Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405093/
https://www.ncbi.nlm.nih.gov/pubmed/36035090
http://dx.doi.org/10.1016/j.phro.2022.08.004
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