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Generation of hepatoma cell lines deficient in microsomal triglyceride transfer protein

The microsomal triglyceride transfer protein (MTP) is essential for the secretion of apolipoprotein B (apoB)48- and apoB100-containing lipoproteins in the intestine and liver, respectively. Loss of function mutations in MTP cause abetalipoproteinemia. Heterologous cells are used to evaluate the func...

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Detalles Bibliográficos
Autores principales: Anaganti, Narasimha, Chattopadhyay, Atrayee, Poirier, John T., Hussain, M. Mahmood
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405095/
https://www.ncbi.nlm.nih.gov/pubmed/35931202
http://dx.doi.org/10.1016/j.jlr.2022.100257