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Generation of hepatoma cell lines deficient in microsomal triglyceride transfer protein
The microsomal triglyceride transfer protein (MTP) is essential for the secretion of apolipoprotein B (apoB)48- and apoB100-containing lipoproteins in the intestine and liver, respectively. Loss of function mutations in MTP cause abetalipoproteinemia. Heterologous cells are used to evaluate the func...
Autores principales: | Anaganti, Narasimha, Chattopadhyay, Atrayee, Poirier, John T., Hussain, M. Mahmood |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405095/ https://www.ncbi.nlm.nih.gov/pubmed/35931202 http://dx.doi.org/10.1016/j.jlr.2022.100257 |
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