Direct Interaction between N-Acetylcysteine and Cytotoxic Electrophile—An Overlooked In Vitro Mechanism of Protection

In laboratory experiments, many electrophilic cytotoxic agents induce cell death accompanied by reactive oxygen species (ROS) production and/or by glutathione (GSH) depletion. Not surprisingly, millimolar concentrations of N-acetylcysteine (NAC), which is used as a universal ROS scavenger and precur...

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Detalles Bibliográficos
Autor principal: Mlejnek, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405167/
https://www.ncbi.nlm.nih.gov/pubmed/36009205
http://dx.doi.org/10.3390/antiox11081485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405167/
https://www.ncbi.nlm.nih.gov/pubmed/36009205
http://dx.doi.org/10.3390/antiox11081485

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