Cargando…

Distinct Roles of Nrf1 and Nrf2 in Monitoring the Reductive Stress Response to Dithiothreitol (DTT)

Transcription factor Nrf2 (nuclear factor, erythroid 2-like 2, encoded by Nfe2l2) has been accepted as a key player in redox regulatory responses to oxidative or reductive stresses. However, relatively little is known about the potential role of Nrf1 (nuclear factor, erythroid 2-like 1, encoded by N...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wufuer, Reziyamu, Fan, Zhuo, Yuan, Jianxin, Zheng, Ze, Hu, Shaofan, Sun, Guiyin, Zhang, Yiguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405177/ https://www.ncbi.nlm.nih.gov/pubmed/36009254 http://dx.doi.org/10.3390/antiox11081535

Ejemplares similares

Differential Yet Integral Contributions of Nrf1 and Nrf2 in the Human HepG2 Cells on Antioxidant Cytoprotective Response against Tert-Butylhydroquinone as a Pro-Oxidative Stressor
por: Wufuer, Reziyamu, et al.
Publicado: (2021)

Toxicity of Dithiothreitol (DTT) to Drosophila melanogaster
por: Wang, Yiwen, et al.
Publicado: (2020)

Nrf1 is an indispensable redox-determining factor for mitochondrial homeostasis by integrating multi-hierarchical regulatory networks
por: Hu, Shaofan, et al.
Publicado: (2022)

A Chemosensor Based on Gold Nanoparticles and Dithiothreitol (DTT) for Acrylamide Electroanalysis
por: Alam, Shahenvaz, et al.
Publicado: (2021)

Unification of Opposites between Two Antioxidant Transcription Factors Nrf1 and Nrf2 in Mediating Distinct Cellular Responses to the Endoplasmic Reticulum Stressor Tunicamycin
por: Zhu, Yu-ping, et al.
Publicado: (2019)

Different Inhibition of Nrf2 by Two Keap1 Isoforms α and β to Shape Malignant Behaviour of Human Hepatocellular Carcinoma
por: Chen, Feilong, et al.
Publicado: (2022)

Nrf1 is not a direct target gene of SREBP1, albeit both are integrated into the rapamycin-responsive regulatory network in human hepatoma cells
por: Liu, Keli, et al.
Publicado: (2023)

A simple method to increase the proportion of bone marrow-derived macrophages positive for M-CSFR using the reducing agent dithiothreitol (DTT)
por: Hashimoto, Ryota, et al.
Publicado: (2018)

Structural and Functional Insights Into Skl and Pal Endolysins, Two Cysteine-Amidases With Anti-pneumococcal Activity. Dithiothreitol (DTT) Effect on Lytic Activity
por: Gallego-Páramo, Cristina, et al.
Publicado: (2021)

Synergism and Antagonism of Two Distinct, but Confused, Nrf1 Factors in Integral Regulation of the Nuclear-to-Mitochondrial Respiratory and Antioxidant Transcription Networks
por: Zhang, Shuwei, et al.
Publicado: (2020)

Commentary: Dithiothreitol (DTT), When Used as Biofilm Detaching Method to Diagnose Implant-Associated Infections, Does Not Affect Microorganisms' Viability, According to the Current Literature
por: Drago, Lorenzo, et al.
Publicado: (2022)

Oncolysis with DTT-205 and DTT-304 generates immunological memory in cured animals
por: Zhou, Heng, et al.
Publicado: (2018)

TCF11 Has a Potent Tumor-Repressing Effect Than Its Prototypic Nrf1α by Definition of Both Similar Yet Different Regulatory Profiles, With a Striking Disparity From Nrf2
por: Wang, Meng, et al.
Publicado: (2021)

Oncogenic Activation of Nrf2, Though as a Master Antioxidant Transcription Factor, Liberated by Specific Knockout of the Full-Length Nrf1α that Acts as a Dominant Tumor Repressor
por: Qiu, Lu, et al.
Publicado: (2018)

Nrf1D Is the First Candidate Secretory Transcription Factor in the Blood Plasma, Its Precursor Existing as a Unique Redox-Sensitive Transmembrane CNC-bZIP Protein in Hemopoietic and Somatic Tissues
por: Yuan, Jianxin, et al.
Publicado: (2018)

Glucose Starvation-Induced Rapid Death of Nrf1α-Deficient, but Not Nrf2-Deficient, Hepatoma Cells Results from Its Fatal Defects in the Redox Metabolism Reprogramming
por: Zhu, Yu-ping, et al.
Publicado: (2020)

The Effects of Dithiothreitol on DNA
por: Fjelstrup, Søren, et al.
Publicado: (2017)

INHIBITION OF NUCLEAR RECONSTRUCTION BY DITHIOTHREITOL
por: Wolfe, Jason, et al.
Publicado: (1974)

Distinct isoforms of Nrf1 diversely regulate different subsets of its cognate target genes
por: Wang, Meng, et al.
Publicado: (2019)

Parent Implementation of DTT Following Telehealth Instruction
por: Gauert, Spencer, et al.
Publicado: (2022)

Oncolytic peptides DTT-205 and DTT-304 induce complete regression and protective immune response in experimental murine colorectal cancer
por: Fleten, Karianne Giller, et al.
Publicado: (2021)

The Role of MicroRNA in the Regulation of Tumor Epithelial–Mesenchymal Transition
por: Feng, Jing, et al.
Publicado: (2022)

Time-course proteomics dataset monitoring HeLa cells subjected to DTT induced endoplasmic reticulum stress
por: Cheng, Zhe, et al.
Publicado: (2016)

Nrf1 and Nrf2 Transcription Factors Regulate Androgen Receptor Transactivation in Prostate Cancer Cells
por: Schultz, Michelle A., et al.
Publicado: (2014)

Nrf2, stress and aging
por: Trougakos, Ioannis P.
Publicado: (2019)

The Protection of Hepatocyte Cells from the Effects of Oxidative Stress by Treatment with Vitamin E in Conjunction with DTT
por: Tsai, Jen-Hsiang, et al.
Publicado: (2010)

Value of monitoring Nrf2 activity for the detection of chemical and oxidative stress
por: Mutter, Fiona E., et al.
Publicado: (2015)

Injury of the optic radiation in patients with mild TBI: A DTT study
por: Jang, Sung Ho, et al.
Publicado: (2020)

HDL functionality is dependent on hepatocyte stress defense factors Nrf1 and Nrf2
por: Trites, Michael J., et al.
Publicado: (2023)

Dithiothreitol and the translocation of preprolactin across mammalian endoplasmic reticulum
Publicado: (1987)

Effects of Dithiothreitol on Fertilization and Early Development in Sea Urchin
por: Limatola, Nunzia, et al.
Publicado: (2021)

Electrocatalytic Depolymerization of Self-Immolative Poly(Dithiothreitol) Derivatives
por: Hansen-Felby, Magnus, et al.
Publicado: (2022)

The selective post-translational processing of transcription factor Nrf1 yields distinct isoforms that dictate its ability to differentially regulate gene expression
por: Zhang, Yiguo, et al.
Publicado: (2015)

Dithiothreitol Affects the Fertilization Response in Immature and Maturing Starfish Oocytes
por: Limatola, Nunzia, et al.
Publicado: (2023)

The membrane-topogenic vectorial behaviour of Nrf1 controls its post-translational modification and transactivation activity
por: Zhang, Yiguo, et al.
Publicado: (2013)

The Nrf1 and Nrf2 Balance in Oxidative Stress Regulation and Androgen Signaling in Prostate Cancer Cells
por: Schultz, Michelle A., et al.
Publicado: (2010)

The C-Terminal Domain of Nrf1 Negatively Regulates the Full-Length CNC-bZIP Factor and Its Shorter Isoform LCR-F1/Nrf1β; Both Are Also Inhibited by the Small Dominant-Negative Nrf1γ/δ Isoforms that Down-Regulate ARE-Battery Gene Expression
por: Zhang, Yiguo, et al.
Publicado: (2014)

Myopathic Lamin Mutations Cause Reductive Stress and Activate the Nrf2/Keap-1 Pathway
por: Dialynas, George, et al.
Publicado: (2015)

Identification of Nrf2-responsive microRNA networks as putative mediators of myocardial reductive stress
por: Quiles, Justin M., et al.
Publicado: (2021)

Defining the Functional Targets of Cap‘n’collar Transcription Factors NRF1, NRF2, and NRF3
por: Ibrahim, Lara, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_3mf533q6eg45p2bfnoh2h7dmr8