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The Generation of Dual-Targeting Fusion Protein PD-L1/CD47 for the Inhibition of Triple-Negative Breast Cancer

Triple-negative breast cancer (TNBC) is a highly aggressive subset of breast cancer with limited therapeutic options. However, its immune evasion mechanisms, characterized by the over-expression of the immune checkpoint molecules PD-L1 and CD47, can be targeted in order to facilitate cancer eliminat...

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Detalles Bibliográficos
Autores principales: Bian, Yanlin, Lin, Tong, Jakos, Tanja, Xiao, Xiaodong, Zhu, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405206/
https://www.ncbi.nlm.nih.gov/pubmed/36009390
http://dx.doi.org/10.3390/biomedicines10081843

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