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Investigation of the Hydrogen Sulfide Signaling Pathway in Schwann Cells during Peripheral Nerve Degeneration: Multi-Omics Approaches

N-ethylmaleimide (NEM) inhibits peripheral nerve degeneration (PND) by targeting Schwann cells in a hydrogen sulfide (H(2)S)-pathway-dependent manner, but the underlying molecular and pharmacological mechanisms are unclear. We investigated the effect of NEM, an α,β-unsaturated carboxyl compound, on...

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Detalles Bibliográficos
Autores principales: Chun, Yoo Lim, Eom, Won-Joon, Lee, Jun Hyung, Nguyen, Thy N. C., Park, Ki-Hoon, Chung, Hyung-Joo, Seo, Han, Huh, Youngbuhm, Kim, Sang Hoon, Yeo, Seung Geun, Park, Wonseok, Bang, Geul, Kim, Jin Young, Kim, Min-Sik, Jeong, Na Young, Jung, Junyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405209/
https://www.ncbi.nlm.nih.gov/pubmed/36009325
http://dx.doi.org/10.3390/antiox11081606