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Neuroprotective Role of α-Lipoic Acid in Iron-Overload-Mediated Toxicity and Inflammation in In Vitro and In Vivo Models
Hemoglobin and iron overload is considered the major contributor to intracerebral hemorrhage (ICH)-induced brain injury. Accumulation of iron in the brain leads to microglia activation, inflammation and cell loss. Current available treatments for iron overload-mediated disorders are characterized by...
Autores principales: | Carota, Giuseppe, Distefano, Alfio, Spampinato, Mariarita, Giallongo, Cesarina, Broggi, Giuseppe, Longhitano, Lucia, Palumbo, Giuseppe A., Parenti, Rosalba, Caltabiano, Rosario, Giallongo, Sebastiano, Di Rosa, Michelino, Polosa, Riccardo, Bramanti, Vincenzo, Vicario, Nunzio, Li Volti, Giovanni, Tibullo, Daniele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405239/ https://www.ncbi.nlm.nih.gov/pubmed/36009316 http://dx.doi.org/10.3390/antiox11081596 |
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