Anterior Mandibular Displacement in Growing Rats—A Systematic Review

SIMPLE SUMMARY: Mandibular deficiency is a very common orthodontic problem. Many different types of appliances have been utilized to correct such malocclusions. Most are appliances that alter the function of the mandible resulting in a more forward positioning of the lower jaw. Many researchers state that such an alteration results in a different rate of mandibular growth, due to condyle endochondral ossification, thus correcting the orthodontic anomaly. Their effect though remains controversial. The aim of the present study was to investigate the effect of such functional appliances in the mandible of growing rats by reviewing the existing literature up to March of 2022. Most of them stated that true condylar growth is observed, although there are many limitations due to the nature of such experiments. ABSTRACT: Skeletal Class II malocclusion is the most common skeletal anomaly in orthodontics. Growth in the body of the deficient mandible is induced by periosteal apposition and endochondral ossification in the condyle. Functional appliances have been used in the correction of Class II malocclusions by inducing mandibular growth. Despite their utilization though, their effect still remains controversial. The aim of the present study is to review the existing literature regarding the effects of mandibular protrusion in mandibular growth of growing rats. A protocol was followed according to the guidelines of the Cohrane Handbook for Systematic Reviews. Databases were searched using a specific algorithm. From the ten studies finally analyzed, we conclude that the use of a functional appliance in growing rats induces cell proliferation and bone formation in their condyles, resulting in mandibular growth.