Cargando…

Antimicrobial Resistance and Its Spread Is a Global Threat

Antimicrobial resistance (AMR) is a challenge to human wellbeing the world over and is one of the more serious public health concerns. AMR has the potential to emerge as a serious healthcare threat if left unchecked, and could put into motion another pandemic. This establishes the need for the estab...

Descripción completa

Detalles Bibliográficos
Autor principal: Aljeldah, Mohammed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405321/
https://www.ncbi.nlm.nih.gov/pubmed/36009948
http://dx.doi.org/10.3390/antibiotics11081082
_version_ 1784773852173172736
author Aljeldah, Mohammed M.
author_facet Aljeldah, Mohammed M.
author_sort Aljeldah, Mohammed M.
collection PubMed
description Antimicrobial resistance (AMR) is a challenge to human wellbeing the world over and is one of the more serious public health concerns. AMR has the potential to emerge as a serious healthcare threat if left unchecked, and could put into motion another pandemic. This establishes the need for the establishment of global health solutions around AMR, taking into account microdata from different parts of the world. The positive influences in this regard could be establishing conducive social norms, charting individual and group behavior practices that favor global human health, and lastly, increasing collective awareness around the need for such action. Apart from being an emerging threat in the clinical space, AMR also increases treatment complexity, posing a real challenge to the existing guidelines around the management of antibiotic resistance. The attribute of resistance development has been linked to many genetic elements, some of which have complex transmission pathways between microbes. Beyond this, new mechanisms underlying the development of AMR are being discovered, making this field an important aspect of medical microbiology. Apart from the genetic aspects of AMR, other practices, including misdiagnosis, exposure to broad-spectrum antibiotics, and lack of rapid diagnosis, add to the creation of resistance. However, upgrades and innovations in DNA sequencing technologies with bioinformatics have revolutionized the diagnostic industry, aiding the real-time detection of causes of AMR and its elements, which are important to delineating control and prevention approaches to fight the threat.
format Online
Article
Text
id pubmed-9405321
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-94053212022-08-26 Antimicrobial Resistance and Its Spread Is a Global Threat Aljeldah, Mohammed M. Antibiotics (Basel) Review Antimicrobial resistance (AMR) is a challenge to human wellbeing the world over and is one of the more serious public health concerns. AMR has the potential to emerge as a serious healthcare threat if left unchecked, and could put into motion another pandemic. This establishes the need for the establishment of global health solutions around AMR, taking into account microdata from different parts of the world. The positive influences in this regard could be establishing conducive social norms, charting individual and group behavior practices that favor global human health, and lastly, increasing collective awareness around the need for such action. Apart from being an emerging threat in the clinical space, AMR also increases treatment complexity, posing a real challenge to the existing guidelines around the management of antibiotic resistance. The attribute of resistance development has been linked to many genetic elements, some of which have complex transmission pathways between microbes. Beyond this, new mechanisms underlying the development of AMR are being discovered, making this field an important aspect of medical microbiology. Apart from the genetic aspects of AMR, other practices, including misdiagnosis, exposure to broad-spectrum antibiotics, and lack of rapid diagnosis, add to the creation of resistance. However, upgrades and innovations in DNA sequencing technologies with bioinformatics have revolutionized the diagnostic industry, aiding the real-time detection of causes of AMR and its elements, which are important to delineating control and prevention approaches to fight the threat. MDPI 2022-08-09 /pmc/articles/PMC9405321/ /pubmed/36009948 http://dx.doi.org/10.3390/antibiotics11081082 Text en © 2022 by the author. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Aljeldah, Mohammed M.
Antimicrobial Resistance and Its Spread Is a Global Threat
title Antimicrobial Resistance and Its Spread Is a Global Threat
title_full Antimicrobial Resistance and Its Spread Is a Global Threat
title_fullStr Antimicrobial Resistance and Its Spread Is a Global Threat
title_full_unstemmed Antimicrobial Resistance and Its Spread Is a Global Threat
title_short Antimicrobial Resistance and Its Spread Is a Global Threat
title_sort antimicrobial resistance and its spread is a global threat
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405321/
https://www.ncbi.nlm.nih.gov/pubmed/36009948
http://dx.doi.org/10.3390/antibiotics11081082
work_keys_str_mv AT aljeldahmohammedm antimicrobialresistanceanditsspreadisaglobalthreat