Sacubitril/Valsartan and Ivabradine Attenuate Left Ventricular Remodelling and Dysfunction in Spontaneously Hypertensive Rats: Different Interactions with the Renin–Angiotensin–Aldosterone System

This study investigated whether sacubitril/valsartan and ivabradine are able to prevent left ventricular (LV) fibrotic remodelling and dysfunction in a rat experimental model of spontaneous hypertension (spontaneously hypertensive rats, SHRs) and whether this potential protection is associated with...

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Detalles Bibliográficos
Autores principales: Simko, Fedor, Baka, Tomas, Stanko, Peter, Repova, Kristina, Krajcirovicova, Kristina, Aziriova, Silvia, Domenig, Oliver, Zorad, Stefan, Adamcova, Michaela, Paulis, Ludovit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405404/
https://www.ncbi.nlm.nih.gov/pubmed/36009391
http://dx.doi.org/10.3390/biomedicines10081844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405404/
https://www.ncbi.nlm.nih.gov/pubmed/36009391
http://dx.doi.org/10.3390/biomedicines10081844

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