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New Pyrazolo-Benzimidazole Mannich Bases with Antimicrobial and Antibiofilm Activities

A new series of pyrazolo-benzimidazole hybrid Mannich bases were synthesized, characterized by (1)H-NMR, (13)C-NMR, IR, UV-Vis, MS, and elemental analysis. In vitro cytotoxicity of the new compounds studied on fibroblast cells showed that the newly synthesized pyrazolo-benzimidazole hybrid derivativ...

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Detalles Bibliográficos
Autores principales: Zalaru, Christina, Dumitrascu, Florea, Draghici, Constantin, Tarcomnicu, Isabela, Marinescu, Maria, Nitulescu, George Mihai, Tatia, Rodica, Moldovan, Lucia, Popa, Marcela, Chifiriuc, Mariana Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405415/
https://www.ncbi.nlm.nih.gov/pubmed/36009963
http://dx.doi.org/10.3390/antibiotics11081094