Cargando…

New Pyrazolo-Benzimidazole Mannich Bases with Antimicrobial and Antibiofilm Activities

A new series of pyrazolo-benzimidazole hybrid Mannich bases were synthesized, characterized by (1)H-NMR, (13)C-NMR, IR, UV-Vis, MS, and elemental analysis. In vitro cytotoxicity of the new compounds studied on fibroblast cells showed that the newly synthesized pyrazolo-benzimidazole hybrid derivativ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zalaru, Christina, Dumitrascu, Florea, Draghici, Constantin, Tarcomnicu, Isabela, Marinescu, Maria, Nitulescu, George Mihai, Tatia, Rodica, Moldovan, Lucia, Popa, Marcela, Chifiriuc, Mariana Carmen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405415/ https://www.ncbi.nlm.nih.gov/pubmed/36009963 http://dx.doi.org/10.3390/antibiotics11081094

Ejemplares similares

Synthesis, density functional theory study and in vitro antimicrobial evaluation of new benzimidazole Mannich bases
por: Marinescu, Maria, et al.
Publicado: (2020)

Ultrasound Assisted Extraction of Saponins from Hedera helix L. and an In Vitro Biocompatibility Evaluation of the Extracts
por: Gavrila, Adina I., et al.
Publicado: (2022)

Synthesis of 1-(2-Fluorophenyl)pyrazoles by 1,3-Dipolar Cycloaddition of the Corresponding Sydnones
por: Dumitrescu, Denisa, et al.
Publicado: (2021)

New Potential Antitumor Pyrazole Derivatives: Synthesis and Cytotoxic Evaluation
por: Nitulescu, George Mihai, et al.
Publicado: (2013)

Introducing chirality in halogenated 3-arylsydnones and their corresponding 1-arylpyrazoles obtained by 1,3-dipolar cycloaddition
por: Popa, Marcel Mirel, et al.
Publicado: (2020)

Synthesis and Toxicity Evaluation of New Pyrroles Obtained by the Reaction of Activated Alkynes with 1-Methyl-3-(cyanomethyl)benzimidazolium Bromide
por: Ivan, Beatrice-Cristina, et al.
Publicado: (2021)

Synthesis X-ray Structure of a New Pyrrolo[1,2-b]-pyridazine Derivative
por: Caira, Mino R., et al.
Publicado: (2005)

Indolizines and pyrrolo[1,2-c]pyrimidines decorated with a pyrimidine and a pyridine unit respectively
por: Popa, Marcel Mirel, et al.
Publicado: (2015)

Novel Strigolactone Mimics That Modulate Photosynthesis and Biomass Accumulation in Chlorella sorokiniana
por: Popa, Daria Gabriela, et al.
Publicado: (2023)

Green Extraction Techniques of Phytochemicals from Hedera helix L. and In Vitro Characterization of the Extracts
por: Gavrila, Adina I., et al.
Publicado: (2023)

Sydnone C-4 heteroarylation with an indolizine ring via Chichibabin indolizine synthesis
por: Albota, Florin, et al.
Publicado: (2016)

Synthesis, In Silico and In Vitro Evaluation of Antimicrobial and Toxicity Features of New 4-[(4-Chlorophenyl)sulfonyl]benzoic Acid Derivatives
por: Apostol, Theodora-Venera, et al.
Publicado: (2021)

Synthesis, Characterization and Cytotoxic Evaluation of New Pyrrolo[1,2-b]pyridazines Obtained via Mesoionic Oxazolo-Pyridazinones
por: Ivan, Beatrice-Cristina, et al.
Publicado: (2023)

New O-Aryl-Carbamoyl-Oxymino-Fluorene Derivatives with MI-Crobicidal and Antibiofilm Activity Enhanced by Combination with Iron Oxide Nanoparticles
por: Vlad, Ilinca Margareta, et al.
Publicado: (2021)

The Redox-Mannich Reaction
por: Chen, Weijie, et al.
Publicado: (2014)

Hybrid magnetite nanoparticles/Rosmarinus officinalis essential oil nanobiosystem with antibiofilm activity
por: Chifiriuc, Carmen, et al.
Publicado: (2012)

In Silico and Experimental Investigation of the Biological Potential of Some Recently Developed Carprofen Derivatives
por: Dumitrascu, Florea, et al.
Publicado: (2022)

Insights into the Microbicidal, Antibiofilm, Antioxidant and Toxicity Profile of New O-Aryl-Carbamoyl-Oxymino-Fluorene Derivatives
por: Vlad, Ilinca Margareta, et al.
Publicado: (2023)

New Pyrrole Derivatives as Promising Biological Agents: Design, Synthesis, Characterization, In Silico, and Cytotoxicity Evaluation
por: Ivan, Beatrice-Cristina, et al.
Publicado: (2022)

Recent advances in the use of benzimidazoles as corrosion inhibitors
por: Marinescu, Maria
Publicado: (2019)

Study of 2-aminoquinolin-4(1H)-one under Mannich and retro-Mannich reaction
por: Funk, Petr, et al.
Publicado: (2017)

Synthesis of Antimicrobial Benzimidazole–Pyrazole Compounds and Their Biological Activities
por: Marinescu, Maria
Publicado: (2021)

New N-acyl Thiourea Derivatives: Synthesis, Standardized Quantification Method and In Vitro Evaluation of Potential Biological Activities
por: Roman, Roxana, et al.
Publicado: (2023)

Repurposing anti-inflammatory drugs for fighting planktonic and biofilm growth. New carbazole derivatives based on the NSAID carprofen: synthesis, in silico and in vitro bioevaluation
por: Dumitrascu, Florea, et al.
Publicado: (2023)

Biological Activity of Triazolopyrimidine Copper(II) Complexes Modulated by an Auxiliary N-N-Chelating Heterocycle Ligands
por: Ruta, Lavinia L., et al.
Publicado: (2021)

Bacteriocins in the Era of Antibiotic Resistance: Rising to the Challenge
por: Gradisteanu Pircalabioru, Gratiela, et al.
Publicado: (2021)

New Nanostructured Materials Based on Mesoporous Silica Loaded with Ru(II)/Ru(III) Complexes with Anticancer and Antimicrobial Properties
por: Marinescu, Gabriela, et al.
Publicado: (2023)

Benzimidazole-Triazole Hybrids as Antimicrobial and Antiviral Agents: A Systematic Review
por: Marinescu, Maria
Publicado: (2023)

Organometallic 3-(1H-Benzimidazol-2-yl)-1H-pyrazolo[3,4-b]pyridines as Potential Anticancer Agents
por: Stepanenko, Iryna N., et al.
Publicado: (2011)

Synthesis and Anticancer Evaluation of New 1,3,4-Oxadiazole Derivatives
por: Stecoza, Camelia Elena, et al.
Publicado: (2021)

Studies on the Anthelmintic Property of Aminobenzylated Mannich Bases
por: Chaluvaraju, KC, et al.
Publicado: (2011)

Iridium-Catalyzed Reductive Nitro-Mannich Cyclization
por: Gregory, Alex W, et al.
Publicado: (2015)

Mannich Bases: An Important Pharmacophore in Present Scenario
por: Bala, Suman, et al.
Publicado: (2014)

Mannich bases in medicinal chemistry and drug design
por: Roman, Gheorghe
Publicado: (2015)

Three-component radical homo Mannich reaction
por: Shi, Shuai, et al.
Publicado: (2021)

Enantio- and diastereoselective conjugate borylation/Mannich cyclization
por: Larin, Egor M., et al.
Publicado: (2020)

X-ray Crystal Structure, Geometric Isomerism, and Antimicrobial Activity of New Copper(II) Carboxylate Complexes with Imidazole Derivatives
por: Vlaicu, Ioana Dorina, et al.
Publicado: (2018)

Glycerol as an Efficient Medium for the Petasis Borono–Mannich Reaction
por: Rosholm, Tomi, et al.
Publicado: (2015)

Asymmetric Catalytic Ketimine Mannich Reactions and Related Transformations
por: Xu, Changgong, et al.
Publicado: (2021)

Recent advances and prospects in the Zn-catalysed Mannich reaction
por: Shamna, Salahudeen, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_8vekqlrsf1bm966c8aqgltku6t