Cargando…

Anticonvulsant Action and Long-Term Effects of Chronic Cannabidiol Treatment in the Rat Pentylenetetrazole-Kindling Model of Epilepsy

Cannabidiol (CBD) showed anticonvulsant action in several preclinical models and is currently approved by regulatory agencies to treat childhood epilepsy syndromes. However, CBD treatment has limited benefits, and its long-term effects on cognition are not fully understood yet. This study aimed to e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gáll, Zsolt, Kelemen, Krisztina, Tolokán, Andrea, Zolcseak, István, Sável, István, Bod, Réka, Ferencz, Elek, Vancea, Szende, Urkon, Melinda, Kolcsár, Melinda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405483/ https://www.ncbi.nlm.nih.gov/pubmed/36009358 http://dx.doi.org/10.3390/biomedicines10081811

Ejemplares similares

Effects of Chronic Cannabidiol Treatment in the Rat Chronic Unpredictable Mild Stress Model of Depression
por: Gáll, Zsolt, et al.
Publicado: (2020)

Anticonvulsant Effects of Dingxian Pill in Pentylenetetrazol-Kindled Rats
por: Zhu, Yudan, et al.
Publicado: (2019)

Anticonvulsant and Neuroprotective Activities of Phragmanthera austroarabica Extract in Pentylenetetrazole-Kindled Mice
por: Aldawsari, Hibah M., et al.
Publicado: (2017)

Anticonvulsant and Antioxidant Effects of Pitavastatin Against Pentylenetetrazol-Induced Kindling in Mice
por: Faghihi, Nastaran, et al.
Publicado: (2017)

Vitamin D Status Assessment: Lack of Correlation between Serum and Hair 25-Hydroxycholecalciferol Levels in Healthy Young Adults
por: Gáll, Zsolt, et al.
Publicado: (2022)

The Applicability of Chromatographic Retention Modeling on Chiral Stationary Phases in Reverse-Phase Mode: A Case Study for Ezetimibe and Its Impurities
por: Ferencz, Elek, et al.
Publicado: (2023)

Eslicarbazepine, but Not Lamotrigine or Ranolazine, Shows Anticonvulsant Efficacy in Carbamazepine-Resistant Rats Developed by Window-Pentylenetetrazole Kindling
por: Zavala-Tecuapetla, Cecilia, et al.
Publicado: (2022)

Sinomenine exerts anticonvulsant profile and neuroprotective activity in pentylenetetrazole kindled rats: involvement of inhibition of NLRP1 inflammasome
por: Gao, Bo, et al.
Publicado: (2018)

Montelukast reduces seizures in pentylenetetrazol-kindled mice
por: Fleck, J., et al.
Publicado: (2016)

Anticonvulsive evaluation of THIP in the murine pentylenetetrazole kindling model: lack of anticonvulsive effect of THIP despite functional δ‐subunit‐containing GABA(A) receptors in dentate gyrus granule cells
por: Simonsen, Charlotte, et al.
Publicado: (2017)

Amomum tsaoko fruit extract exerts anticonvulsant effects through suppression of oxidative stress and neuroinflammation in a pentylenetetrazol kindling model of epilepsy in mice
por: Wang, Kaina, et al.
Publicado: (2021)

Effects of Lycopene and Sodium Valproate on Pentylenetetrazol-Induced Kindling in Mice
por: Kumar, Vinay, et al.
Publicado: (2016)

Relationship between Serum 25-Hydroxyvitamin D Levels and Hormonal Status in Infertile Women: A Retrospective Study
por: Kolcsár, Melinda, et al.
Publicado: (2023)

Resveratrol is Neuroprotective and Improves Cognition in Pentylenetetrazole-kindling Model of Epilepsy in Rats
por: Meng, X. J., et al.
Publicado: (2014)

Antiepileptic and Antioxidant Effect of Brassica nigra on Pentylenetetrazol-Induced Kindling in Mice
por: Kiasalari, Zahra, et al.
Publicado: (2012)

Ferroptosis Induction in Pentylenetetrazole Kindling and Pilocarpine-Induced Epileptic Seizures in Mice
por: Mao, Xiao-Yuan, et al.
Publicado: (2019)

Effect of lamotrigine on seizure development in a rat pentylenetetrazole kindling model
por: Chen, Yishu, et al.
Publicado: (2017)

Investigating Cardiac Morphological Alterations in a Pentylenetetrazol-Kindling Model of Epilepsy
por: Akyuz, Enes, et al.
Publicado: (2020)

Anticonvulsive Effects and Pharmacokinetic Profile of Cannabidiol (CBD) in the Pentylenetetrazol (PTZ) or N-Methyl-D-Aspartate (NMDA) Models of Seizures in Infantile Rats
por: Uttl, Libor, et al.
Publicado: (2021)

The Anticonvulsant Effects of SR 57227 on Pentylenetetrazole-Induced Seizure in Mice
por: Li, Bingjin, et al.
Publicado: (2014)

Anticonvulsant Effect of Guaifenesin against Pentylenetetrazol-Induced Seizure in Mice
por: Keshavarz, Mojtaba, et al.
Publicado: (2013)

Paradoxical Anticonvulsant Effect of Cefepime in the Pentylenetetrazole Model of Seizures in Rats
por: Amakhin, Dmitry V., et al.
Publicado: (2020)

Behavioral and Neurochemical Consequences of Pentylenetetrazol-Induced Kindling in Young and Middle-Aged Rats
por: Hoeller, Alexandre Ademar, et al.
Publicado: (2017)

Effects of GLP-1 Receptor Activation on a Pentylenetetrazole—Kindling Rat Model
por: Hussein, Abdelaziz M., et al.
Publicado: (2019)

Alteration of Extracellular Matrix Molecules and Perineuronal Nets in the Hippocampus of Pentylenetetrazol-Kindled Mice
por: Ueno, Hiroshi, et al.
Publicado: (2019)

Behavioral and Brain Structural Changes in Kindled Rats Induced by Coriaria Lactone/Pentylenetetrazol
por: He, Shixu, et al.
Publicado: (2021)

Parameters of Oxidative Stress and Behavior in Animals Treated with Dexametasone and Submitted to Pentylenetetrazol Kindling
por: Guzzo, Edson Fernando Muller, et al.
Publicado: (2021)

Effects of Satureja Bachtiarica Essential Oil in Preventing Seizure in Pentylenetetrazol-Kindled Mice
por: Rabiei, Zahra, et al.
Publicado: (2022)

Anti-kindling Effect of Bezafibrate, a Peroxisome Proliferator-activated Receptors Alpha Agonist, in Pentylenetetrazole Induced Kindling Seizure Model
por: Saha, Lekha, et al.
Publicado: (2014)

Anticonvulsant Effect of Alcea aucheri on Pentylenetetrazole and Maximal Electroshock Seizures in Mice
por: Mombeini, Tajmah, et al.
Publicado: (2020)

Anticonvulsive Effects of Chondroitin Sulfate on Pilocarpine and Pentylenetetrazole Induced Epileptogenesis in Mice
por: Singh, Shareen, et al.
Publicado: (2021)

Effects of Cariprazine, Aripiprazole, and Olanzapine on Mouse Fibroblast Culture: Changes in Adiponectin Contents in Supernatants, Triglyceride Accumulation, and Peroxisome Proliferator-Activated Receptor-γ Expression
por: Bába, László-István, et al.
Publicado: (2019)

Amygdala Low-Frequency Stimulation Reduces Pathological Phase-Amplitude Coupling in the Pilocarpine Model of Epilepsy
por: Mihály, István, et al.
Publicado: (2020)

The effect of Zataria multiflora Boiss hydroalcoholic extract and fractions in pentylenetetrazole-induced kindling in mice
por: Shamsizadeh, Ali, et al.
Publicado: (2016)

Potentiation of pentylenetetrazole-induced neuronal damage by dimethyl sulfoxide in chemical kindling model in rats
por: Kumari, Puja, et al.
Publicado: (2018)

Anti-Oxidant and Anti-Apoptotic Effects of Berberine in Pentylenetetrazole-Induced Kindling Model in Rat
por: Guna, Vaishali, et al.
Publicado: (2018)

The Protective Effect of Auraptene Against Oxidative Stress and Pentylenetetrazol-Induced Chemical Kindling in Mice
por: Etemad, Leila, et al.
Publicado: (2019)

Combination of levetiracetam with sodium selenite prevents pentylenetetrazole-induced kindling and behavioral comorbidities in rats
por: Rehman, Zohabia, et al.
Publicado: (2022)

Enhanced Astrocyte Activity and Excitatory Synaptic Function in the Hippocampus of Pentylenetetrazole Kindling Model of Epilepsy
por: Díaz, Franco, et al.
Publicado: (2023)

Potential Mechanisms Involved in the Anticonvulsant Effect of Walnut Extract on Pentylenetetrazole-Induced Seizure
por: Asadi-Shekaari, Majid, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_4cikcs0lks6ho0abl3on9lg72e