An Efficient Method for the Preparation of Sulfonamides from Sodium Sulfinates and Amines

Sulfonamides have a special role on medicine due to their broad biological activities, as bacterial infections, diabetes mellitus, oedema, hypertension prevention and treatment. In addition, sulfonamides are also useful in herbicides and pesticides. Herein, we communicate an efficient strategy for t...

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Detalles Bibliográficos
Autores principales: Tian, Haiying, Li, Ruiyan, Guo, Fang, Chen, Xiuling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405518/
https://www.ncbi.nlm.nih.gov/pubmed/36005567
http://dx.doi.org/10.1002/open.202200097
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author Tian, Haiying
Li, Ruiyan
Guo, Fang
Chen, Xiuling
author_facet Tian, Haiying
Li, Ruiyan
Guo, Fang
Chen, Xiuling
author_sort Tian, Haiying
collection PubMed
description Sulfonamides have a special role on medicine due to their broad biological activities, as bacterial infections, diabetes mellitus, oedema, hypertension prevention and treatment. In addition, sulfonamides are also useful in herbicides and pesticides. Herein, we communicate an efficient strategy for the preparation of sulfonamides via NH(4)I‐mediated amination of sodium sulfinates. This new method provides a general and environmentally friendly access to sulfonamide compounds and tolerates a wide range of functional groups.
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spelling pubmed-94055182022-08-26 An Efficient Method for the Preparation of Sulfonamides from Sodium Sulfinates and Amines Tian, Haiying Li, Ruiyan Guo, Fang Chen, Xiuling ChemistryOpen Research Articles Sulfonamides have a special role on medicine due to their broad biological activities, as bacterial infections, diabetes mellitus, oedema, hypertension prevention and treatment. In addition, sulfonamides are also useful in herbicides and pesticides. Herein, we communicate an efficient strategy for the preparation of sulfonamides via NH(4)I‐mediated amination of sodium sulfinates. This new method provides a general and environmentally friendly access to sulfonamide compounds and tolerates a wide range of functional groups. John Wiley and Sons Inc. 2022-08-25 /pmc/articles/PMC9405518/ /pubmed/36005567 http://dx.doi.org/10.1002/open.202200097 Text en © 2022 The Authors. Published by Wiley-VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Tian, Haiying
Li, Ruiyan
Guo, Fang
Chen, Xiuling
An Efficient Method for the Preparation of Sulfonamides from Sodium Sulfinates and Amines
title An Efficient Method for the Preparation of Sulfonamides from Sodium Sulfinates and Amines
title_full An Efficient Method for the Preparation of Sulfonamides from Sodium Sulfinates and Amines
title_fullStr An Efficient Method for the Preparation of Sulfonamides from Sodium Sulfinates and Amines
title_full_unstemmed An Efficient Method for the Preparation of Sulfonamides from Sodium Sulfinates and Amines
title_short An Efficient Method for the Preparation of Sulfonamides from Sodium Sulfinates and Amines
title_sort efficient method for the preparation of sulfonamides from sodium sulfinates and amines
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405518/
https://www.ncbi.nlm.nih.gov/pubmed/36005567
http://dx.doi.org/10.1002/open.202200097
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