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G-Quadruplex Formed by the Promoter Region of the hTERT Gene: Structure-Driven Effects on DNA Mismatch Repair Functions

G-quadruplexes (G4s) are a unique class of noncanonical DNAs that play a key role in cellular processes and neoplastic transformation. Herein, we focused on the promoter region of human TERT oncogene, whose product is responsible for the immortality of cancer cells. It has been shown by chemical pro...

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Detalles Bibliográficos
Autores principales:	Pavlova, Anzhela V., Savitskaya, Victoria Yu., Dolinnaya, Nina G., Monakhova, Mayya V., Litvinova, Anastasia V., Kubareva, Elena A., Zvereva, Maria I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405553/ https://www.ncbi.nlm.nih.gov/pubmed/36009419 http://dx.doi.org/10.3390/biomedicines10081871

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