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Effects of a Phosphodiesterase inhibitor on the Browning of Adipose Tissue in Mice

Cilostazol is a selective inhibitor of phosphodiesterase type 3 (PDE3) that increases intracellular cyclic adenosine monophosphate (cAMP), which plays a critical role in the development of the beige phenotype and the activation of its thermogenic program in white adipose tissue (WAT). We investigate...

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Detalles Bibliográficos
Autores principales: Seo, Da Hea, Shin, Eugene, Lee, Yong-ho, Park, Se-Eun, Nam, Ki Taek, Kim, Jae-woo, Cha, Bong-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405663/
https://www.ncbi.nlm.nih.gov/pubmed/36009398
http://dx.doi.org/10.3390/biomedicines10081852