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Haematological Drugs Affecting Lipid Metabolism and Vascular Health
Many drugs affect lipid metabolism and have side effects which promote atherosclerosis. The prevalence of cancer-therapy-related cardiovascular (CV) disease is increasing due to development of new drugs and improved survival of patients: cardio-oncology is a new field of interest and research. Moreo...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405726/ https://www.ncbi.nlm.nih.gov/pubmed/36009482 http://dx.doi.org/10.3390/biomedicines10081935 |
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author | Parrella, Antonio Iannuzzi, Arcangelo Annunziata, Mario Covetti, Giuseppe Cavallaro, Raimondo Aliberti, Emilio Tortori, Elena Iannuzzo, Gabriella |
author_facet | Parrella, Antonio Iannuzzi, Arcangelo Annunziata, Mario Covetti, Giuseppe Cavallaro, Raimondo Aliberti, Emilio Tortori, Elena Iannuzzo, Gabriella |
author_sort | Parrella, Antonio |
collection | PubMed |
description | Many drugs affect lipid metabolism and have side effects which promote atherosclerosis. The prevalence of cancer-therapy-related cardiovascular (CV) disease is increasing due to development of new drugs and improved survival of patients: cardio-oncology is a new field of interest and research. Moreover, drugs used in transplanted patients frequently have metabolic implications. Increasingly, internists, lipidologists, and angiologists are being consulted by haematologists for side effects on metabolism (especially lipid metabolism) and arterial circulation caused by drugs used in haematology. The purpose of this article is to review the main drugs used in haematology with side effects on lipid metabolism and atherosclerosis, detailing their mechanisms of action and suggesting the most effective therapies. |
format | Online Article Text |
id | pubmed-9405726 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-94057262022-08-26 Haematological Drugs Affecting Lipid Metabolism and Vascular Health Parrella, Antonio Iannuzzi, Arcangelo Annunziata, Mario Covetti, Giuseppe Cavallaro, Raimondo Aliberti, Emilio Tortori, Elena Iannuzzo, Gabriella Biomedicines Review Many drugs affect lipid metabolism and have side effects which promote atherosclerosis. The prevalence of cancer-therapy-related cardiovascular (CV) disease is increasing due to development of new drugs and improved survival of patients: cardio-oncology is a new field of interest and research. Moreover, drugs used in transplanted patients frequently have metabolic implications. Increasingly, internists, lipidologists, and angiologists are being consulted by haematologists for side effects on metabolism (especially lipid metabolism) and arterial circulation caused by drugs used in haematology. The purpose of this article is to review the main drugs used in haematology with side effects on lipid metabolism and atherosclerosis, detailing their mechanisms of action and suggesting the most effective therapies. MDPI 2022-08-10 /pmc/articles/PMC9405726/ /pubmed/36009482 http://dx.doi.org/10.3390/biomedicines10081935 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Parrella, Antonio Iannuzzi, Arcangelo Annunziata, Mario Covetti, Giuseppe Cavallaro, Raimondo Aliberti, Emilio Tortori, Elena Iannuzzo, Gabriella Haematological Drugs Affecting Lipid Metabolism and Vascular Health |
title | Haematological Drugs Affecting Lipid Metabolism and Vascular Health |
title_full | Haematological Drugs Affecting Lipid Metabolism and Vascular Health |
title_fullStr | Haematological Drugs Affecting Lipid Metabolism and Vascular Health |
title_full_unstemmed | Haematological Drugs Affecting Lipid Metabolism and Vascular Health |
title_short | Haematological Drugs Affecting Lipid Metabolism and Vascular Health |
title_sort | haematological drugs affecting lipid metabolism and vascular health |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405726/ https://www.ncbi.nlm.nih.gov/pubmed/36009482 http://dx.doi.org/10.3390/biomedicines10081935 |
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