A Setmelanotide-like Effect at MC4R Is Achieved by MC4R Dimer Separation

Melanocortin 4 receptor (MC4R) is part of the leptin-melanocortin pathway and plays an essential role in mediating energy homeostasis. Mutations in the MC4R are the most frequent monogenic cause for obesity. Due to increasing numbers of people with excess body weight, the MC4R has become a target of...

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Detalles Bibliográficos
Autores principales: Reininghaus, Nanina, Paisdzior, Sarah, Höpfner, Friederike, Jyrch, Sabine, Cetindag, Cigdem, Scheerer, Patrick, Kühnen, Peter, Biebermann, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405727/
https://www.ncbi.nlm.nih.gov/pubmed/36009013
http://dx.doi.org/10.3390/biom12081119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405727/
https://www.ncbi.nlm.nih.gov/pubmed/36009013
http://dx.doi.org/10.3390/biom12081119

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