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ADAR2 Protein Is Associated with Overall Survival in GBM Patients and Its Decrease Triggers the Anchorage-Independent Cell Growth Signature

Background: Epitranscriptomic mechanisms, such as A-to-I RNA editing mediated by ADAR deaminases, contribute to cancer heterogeneity and patients’ stratification. ADAR enzymes can change the sequence, structure, and expression of several RNAs, affecting cancer cell behavior. In glioblastoma, an over...

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Detalles Bibliográficos
Autores principales: Cesarini, Valeriana, Silvestris, Domenico Alessandro, Galeano, Federica, Tassinari, Valentina, Martini, Maurizio, Locatelli, Franco, Gallo, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405742/
https://www.ncbi.nlm.nih.gov/pubmed/36009036
http://dx.doi.org/10.3390/biom12081142