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Targeting MDM4 as a Novel Therapeutic Approach in Prostate Cancer Independent of p53 Status

SIMPLE SUMMARY: Prostate cancer is the most prevalent male cancer. It poses a survival risk if it spreads and fails treatment. In search of fresh insight into lethal prostate cancers, we examined failures in cancer defence systems operated by the key anticancer protein p53. Normally, levels of p53 a...

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Detalles Bibliográficos
Autores principales: Mejía-Hernández, Javier Octavio, Raghu, Dinesh, Caramia, Franco, Clemons, Nicholas, Fujihara, Kenji, Riseborough, Thomas, Teunisse, Amina, Jochemsen, Aart G., Abrahmsén, Lars, Blandino, Giovanni, Russo, Andrea, Gamell, Cristina, Fox, Stephen B., Mitchell, Catherine, Takano, Elena A., Byrne, David, Miranda, Panimaya Jeffreena, Saleh, Reem, Thorne, Heather, Sandhu, Shahneen, Williams, Scott G., Keam, Simon P., Haupt, Ygal, Haupt, Sue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405814/
https://www.ncbi.nlm.nih.gov/pubmed/36010941
http://dx.doi.org/10.3390/cancers14163947