Cargando…
Robotic Verticalization plus Music Therapy in Chronic Disorders of Consciousness: Promising Results from a Pilot Study
Background: Music stimulation is considered a valuable form of intervention in disorders of consciousness (DoC); for instance, verticalization may improve motor and cognitive recovery. Our purpose is to investigate the effects of a novel rehabilitative approach combining robotic verticalization trai...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405818/ https://www.ncbi.nlm.nih.gov/pubmed/36009107 http://dx.doi.org/10.3390/brainsci12081045 |
_version_ | 1784773970522800128 |
---|---|
author | De Luca, Rosaria Bonanno, Mirjam Vermiglio, Giuliana Trombetta, Giovanni Andidero, Ersilia Caminiti, Angelo Pollicino, Patrizia Rifici, Carmela Calabrò, Rocco Salvatore |
author_facet | De Luca, Rosaria Bonanno, Mirjam Vermiglio, Giuliana Trombetta, Giovanni Andidero, Ersilia Caminiti, Angelo Pollicino, Patrizia Rifici, Carmela Calabrò, Rocco Salvatore |
author_sort | De Luca, Rosaria |
collection | PubMed |
description | Background: Music stimulation is considered a valuable form of intervention in disorders of consciousness (DoC); for instance, verticalization may improve motor and cognitive recovery. Our purpose is to investigate the effects of a novel rehabilitative approach combining robotic verticalization training (RVT) with personalized music stimulation in people with DoC. Methods: Sixteen subjects affected by minimally conscious state due to traumatic brain lesions who attended our Intensive Neuro-Rehabilitation Unit were enrolled in this randomized trial. They received either music robotic verticalization (MRV) using the Erigo device plus a personalized music playlist or only RVT without music stimuli. Each treatment was performed 2 times a week for 8 consecutive weeks in addition to standard neurorehabilitation. Results: We found significant improvements in all patients’ outcomes in the experimental group (who received MRV): Coma Recovery Scale-Revised (CRS-R) (p < 0.01), Level of Cognitive Functioning (LCF) (p < 0.02), Functional Independence Measure (FIM) (p < 0.03), Functional Communication Scale (FCS) (p < 0.007), Trunk Control Test (TCT) (p = 0.05). Significant differences between the two groups were also found in the main outcome measure CRS-R (p < 0.01) but not for TCT and FIM. Conclusions: Our study supports the safety and effectiveness of RVT with the Erigo device in chronic MCS, and the achievement of better outcomes when RVT is combined with music stimulation. |
format | Online Article Text |
id | pubmed-9405818 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-94058182022-08-26 Robotic Verticalization plus Music Therapy in Chronic Disorders of Consciousness: Promising Results from a Pilot Study De Luca, Rosaria Bonanno, Mirjam Vermiglio, Giuliana Trombetta, Giovanni Andidero, Ersilia Caminiti, Angelo Pollicino, Patrizia Rifici, Carmela Calabrò, Rocco Salvatore Brain Sci Article Background: Music stimulation is considered a valuable form of intervention in disorders of consciousness (DoC); for instance, verticalization may improve motor and cognitive recovery. Our purpose is to investigate the effects of a novel rehabilitative approach combining robotic verticalization training (RVT) with personalized music stimulation in people with DoC. Methods: Sixteen subjects affected by minimally conscious state due to traumatic brain lesions who attended our Intensive Neuro-Rehabilitation Unit were enrolled in this randomized trial. They received either music robotic verticalization (MRV) using the Erigo device plus a personalized music playlist or only RVT without music stimuli. Each treatment was performed 2 times a week for 8 consecutive weeks in addition to standard neurorehabilitation. Results: We found significant improvements in all patients’ outcomes in the experimental group (who received MRV): Coma Recovery Scale-Revised (CRS-R) (p < 0.01), Level of Cognitive Functioning (LCF) (p < 0.02), Functional Independence Measure (FIM) (p < 0.03), Functional Communication Scale (FCS) (p < 0.007), Trunk Control Test (TCT) (p = 0.05). Significant differences between the two groups were also found in the main outcome measure CRS-R (p < 0.01) but not for TCT and FIM. Conclusions: Our study supports the safety and effectiveness of RVT with the Erigo device in chronic MCS, and the achievement of better outcomes when RVT is combined with music stimulation. MDPI 2022-08-06 /pmc/articles/PMC9405818/ /pubmed/36009107 http://dx.doi.org/10.3390/brainsci12081045 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article De Luca, Rosaria Bonanno, Mirjam Vermiglio, Giuliana Trombetta, Giovanni Andidero, Ersilia Caminiti, Angelo Pollicino, Patrizia Rifici, Carmela Calabrò, Rocco Salvatore Robotic Verticalization plus Music Therapy in Chronic Disorders of Consciousness: Promising Results from a Pilot Study |
title | Robotic Verticalization plus Music Therapy in Chronic Disorders of Consciousness: Promising Results from a Pilot Study |
title_full | Robotic Verticalization plus Music Therapy in Chronic Disorders of Consciousness: Promising Results from a Pilot Study |
title_fullStr | Robotic Verticalization plus Music Therapy in Chronic Disorders of Consciousness: Promising Results from a Pilot Study |
title_full_unstemmed | Robotic Verticalization plus Music Therapy in Chronic Disorders of Consciousness: Promising Results from a Pilot Study |
title_short | Robotic Verticalization plus Music Therapy in Chronic Disorders of Consciousness: Promising Results from a Pilot Study |
title_sort | robotic verticalization plus music therapy in chronic disorders of consciousness: promising results from a pilot study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405818/ https://www.ncbi.nlm.nih.gov/pubmed/36009107 http://dx.doi.org/10.3390/brainsci12081045 |
work_keys_str_mv | AT delucarosaria roboticverticalizationplusmusictherapyinchronicdisordersofconsciousnesspromisingresultsfromapilotstudy AT bonannomirjam roboticverticalizationplusmusictherapyinchronicdisordersofconsciousnesspromisingresultsfromapilotstudy AT vermigliogiuliana roboticverticalizationplusmusictherapyinchronicdisordersofconsciousnesspromisingresultsfromapilotstudy AT trombettagiovanni roboticverticalizationplusmusictherapyinchronicdisordersofconsciousnesspromisingresultsfromapilotstudy AT andideroersilia roboticverticalizationplusmusictherapyinchronicdisordersofconsciousnesspromisingresultsfromapilotstudy AT caminitiangelo roboticverticalizationplusmusictherapyinchronicdisordersofconsciousnesspromisingresultsfromapilotstudy AT pollicinopatrizia roboticverticalizationplusmusictherapyinchronicdisordersofconsciousnesspromisingresultsfromapilotstudy AT rificicarmela roboticverticalizationplusmusictherapyinchronicdisordersofconsciousnesspromisingresultsfromapilotstudy AT calabroroccosalvatore roboticverticalizationplusmusictherapyinchronicdisordersofconsciousnesspromisingresultsfromapilotstudy |