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Bulk and Surface Acoustic Wave Biosensors for Milk Analysis †

Milk and dairy products are common foods and, therefore, are subject to regular controls. Such controls cover both the identification and quantification of specific components and the determination of physical parameters. Components include the usual milk ingredients, mainly carbohydrates, proteins,...

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Detalles Bibliográficos
Autor principal: Länge, Kerstin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405821/
https://www.ncbi.nlm.nih.gov/pubmed/36005001
http://dx.doi.org/10.3390/bios12080602
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author Länge, Kerstin
author_facet Länge, Kerstin
author_sort Länge, Kerstin
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description Milk and dairy products are common foods and, therefore, are subject to regular controls. Such controls cover both the identification and quantification of specific components and the determination of physical parameters. Components include the usual milk ingredients, mainly carbohydrates, proteins, and fat, and any impurities that may be present. The latter range from small molecules, such as drug residues, to large molecules, e.g., protein-based toxins, to pathogenic microorganisms. Physical parameters of interest include viscosity as an indicator of milk gelation. Bulk and surface acoustic wave sensors, such as quartz crystal microbalance (QCM) and surface acoustic wave (SAW) devices, can principally be used for both types of analysis, with the actual application mainly depending on the device coating and the test format. This review summarizes the achievements of acoustic sensor devices used for milk analysis applications, including the determination of physical liquid parameters and the detection of low- and high-molecular-weight analytes and microorganisms. It is shown how the various requirements resulting from the respective analytes and the complex sample matrix are addressed, and to what extent the analytical demands, e.g., with regard to legal limits, are met.
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spelling pubmed-94058212022-08-26 Bulk and Surface Acoustic Wave Biosensors for Milk Analysis † Länge, Kerstin Biosensors (Basel) Review Milk and dairy products are common foods and, therefore, are subject to regular controls. Such controls cover both the identification and quantification of specific components and the determination of physical parameters. Components include the usual milk ingredients, mainly carbohydrates, proteins, and fat, and any impurities that may be present. The latter range from small molecules, such as drug residues, to large molecules, e.g., protein-based toxins, to pathogenic microorganisms. Physical parameters of interest include viscosity as an indicator of milk gelation. Bulk and surface acoustic wave sensors, such as quartz crystal microbalance (QCM) and surface acoustic wave (SAW) devices, can principally be used for both types of analysis, with the actual application mainly depending on the device coating and the test format. This review summarizes the achievements of acoustic sensor devices used for milk analysis applications, including the determination of physical liquid parameters and the detection of low- and high-molecular-weight analytes and microorganisms. It is shown how the various requirements resulting from the respective analytes and the complex sample matrix are addressed, and to what extent the analytical demands, e.g., with regard to legal limits, are met. MDPI 2022-08-05 /pmc/articles/PMC9405821/ /pubmed/36005001 http://dx.doi.org/10.3390/bios12080602 Text en © 2022 by the author. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Länge, Kerstin
Bulk and Surface Acoustic Wave Biosensors for Milk Analysis †
title Bulk and Surface Acoustic Wave Biosensors for Milk Analysis †
title_full Bulk and Surface Acoustic Wave Biosensors for Milk Analysis †
title_fullStr Bulk and Surface Acoustic Wave Biosensors for Milk Analysis †
title_full_unstemmed Bulk and Surface Acoustic Wave Biosensors for Milk Analysis †
title_short Bulk and Surface Acoustic Wave Biosensors for Milk Analysis †
title_sort bulk and surface acoustic wave biosensors for milk analysis †
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405821/
https://www.ncbi.nlm.nih.gov/pubmed/36005001
http://dx.doi.org/10.3390/bios12080602
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