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Lipoprotein Deprivation Reveals a Cholesterol-Dependent Therapeutic Vulnerability in Diffuse Glioma Metabolism

SIMPLE SUMMARY: High-grade gliomas are aggressive cancers that arise in children and adults, for which there is an urgent need for more effective drug therapies. Targeting the energy requirements (‘metabolism’) of these cancer cells may offer a new avenue for therapy. Cholesterol is a fatty substanc...

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Detalles Bibliográficos
Autores principales:	Wood, James, Abdelrazig, Salah, Evseev, Sergey, Ortori, Catherine, Castellanos-Uribe, Marcos, May, Sean T., Barrett, David A., Diksin, Mohammed, Chakraborty, Sajib, Kim, Dong-Hyun, Grundy, Richard G., Rahman, Ruman
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405833/ https://www.ncbi.nlm.nih.gov/pubmed/36010867 http://dx.doi.org/10.3390/cancers14163873

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