Can PPAR γ Keep Cadmium in Check?

Cd, a naturally occurring endocrine toxin found in tobacco leaves, originates in the environment and enters the body through inhalation, targeting the lungs and kidneys. A study published by Larsen-Carey et al. revealed that cadmium mediates the persistence of classically activated lung macrophages...

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Detalles Bibliográficos
Autores principales: Robinson, Caila, Lockey, Richard F., Kolliputi, Narasaiah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405879/
https://www.ncbi.nlm.nih.gov/pubmed/36008989
http://dx.doi.org/10.3390/biom12081094
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author Robinson, Caila
Lockey, Richard F.
Kolliputi, Narasaiah
author_facet Robinson, Caila
Lockey, Richard F.
Kolliputi, Narasaiah
author_sort Robinson, Caila
collection PubMed
description Cd, a naturally occurring endocrine toxin found in tobacco leaves, originates in the environment and enters the body through inhalation, targeting the lungs and kidneys. A study published by Larsen-Carey et al. revealed that cadmium mediates the persistence of classically activated lung macrophages to exacerbate lung injury. The research discovered a novel role for PPAR γ as an effective regulator for the alternative activation of macrophages in response to Cd and Cd-induced lung injury.
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spelling pubmed-94058792022-08-26 Can PPAR γ Keep Cadmium in Check? Robinson, Caila Lockey, Richard F. Kolliputi, Narasaiah Biomolecules Perspective Cd, a naturally occurring endocrine toxin found in tobacco leaves, originates in the environment and enters the body through inhalation, targeting the lungs and kidneys. A study published by Larsen-Carey et al. revealed that cadmium mediates the persistence of classically activated lung macrophages to exacerbate lung injury. The research discovered a novel role for PPAR γ as an effective regulator for the alternative activation of macrophages in response to Cd and Cd-induced lung injury. MDPI 2022-08-09 /pmc/articles/PMC9405879/ /pubmed/36008989 http://dx.doi.org/10.3390/biom12081094 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Perspective
Robinson, Caila
Lockey, Richard F.
Kolliputi, Narasaiah
Can PPAR γ Keep Cadmium in Check?
title Can PPAR γ Keep Cadmium in Check?
title_full Can PPAR γ Keep Cadmium in Check?
title_fullStr Can PPAR γ Keep Cadmium in Check?
title_full_unstemmed Can PPAR γ Keep Cadmium in Check?
title_short Can PPAR γ Keep Cadmium in Check?
title_sort can ppar γ keep cadmium in check?
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405879/
https://www.ncbi.nlm.nih.gov/pubmed/36008989
http://dx.doi.org/10.3390/biom12081094
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