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The Effect of Fish Oil-Based Foods on Lipid and Oxidative Status Parameters in Police Dogs

The synthesis, degradation, and reconstruction of the cell membrane as a metabolic pathway of phospholipids is a constant and dynamic process. Fatty acids as bioactive lipid components of plasma and erythrocyte phospholipids as structural lipids have biological roles in the integrity of cell membran...

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Autores principales: Ravić, Branko, Debeljak-Martacić, Jasmina, Pokimica, Biljana, Vidović, Nevena, Ranković, Slavica, Glibetić, Marija, Stepanović, Predrag, Popović, Tamara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405924/
https://www.ncbi.nlm.nih.gov/pubmed/36008986
http://dx.doi.org/10.3390/biom12081092
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author Ravić, Branko
Debeljak-Martacić, Jasmina
Pokimica, Biljana
Vidović, Nevena
Ranković, Slavica
Glibetić, Marija
Stepanović, Predrag
Popović, Tamara
author_facet Ravić, Branko
Debeljak-Martacić, Jasmina
Pokimica, Biljana
Vidović, Nevena
Ranković, Slavica
Glibetić, Marija
Stepanović, Predrag
Popović, Tamara
author_sort Ravić, Branko
collection PubMed
description The synthesis, degradation, and reconstruction of the cell membrane as a metabolic pathway of phospholipids is a constant and dynamic process. Fatty acids as bioactive lipid components of plasma and erythrocyte phospholipids as structural lipids have biological roles in the integrity of cell membranes. Fatty acids, depending on the chain length, the degree of saturation, and the synthesis pathways, can alleviate inflammation and oxidative stress caused by excessive exercise. Considering that changing food intake or diet can influence fatty acid phospholipid metabolism, our study aimed to determine the potential benefits of fish-based diets in working (police) dogs undergoing intensive training concerning bioactive lipids such as fatty acids, phospholipids of plasma, and erythrocytes. Fatty acid esters’ composition of plasma and erythrocyte phospholipids as a bioactive lipids, in addition to markers of oxidative stress and metabolic parameters, were analysed by GC chromatography. The food was well tolerated by all dogs, and the compliance to the diet was high throughout the study. After the treatment with fish-based food, blood glucose, total, and LDL cholesterol levels were significantly reduced, indicating positive biochemical profiles of dogs. Correlations of fatty acid phospholipid compositions between plasma and erythrocytes have shown that both plasma and erythrocytes could represent markers of omega-3 eicosapentaenoic and docosahexaenoic acid intake levels in dogs. Morover, fish-based food supplementation caused a significant reduction in lipid peroxidation markers. The enrichment of dogs’ diets with marine fish could improve oxidative status and improve roles and status of bioactive lipids, such as membrane phospholipids and fatty acids, as its components in plasma and erythrocytes in police dogs exposed to intensive exercise.
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spelling pubmed-94059242022-08-26 The Effect of Fish Oil-Based Foods on Lipid and Oxidative Status Parameters in Police Dogs Ravić, Branko Debeljak-Martacić, Jasmina Pokimica, Biljana Vidović, Nevena Ranković, Slavica Glibetić, Marija Stepanović, Predrag Popović, Tamara Biomolecules Article The synthesis, degradation, and reconstruction of the cell membrane as a metabolic pathway of phospholipids is a constant and dynamic process. Fatty acids as bioactive lipid components of plasma and erythrocyte phospholipids as structural lipids have biological roles in the integrity of cell membranes. Fatty acids, depending on the chain length, the degree of saturation, and the synthesis pathways, can alleviate inflammation and oxidative stress caused by excessive exercise. Considering that changing food intake or diet can influence fatty acid phospholipid metabolism, our study aimed to determine the potential benefits of fish-based diets in working (police) dogs undergoing intensive training concerning bioactive lipids such as fatty acids, phospholipids of plasma, and erythrocytes. Fatty acid esters’ composition of plasma and erythrocyte phospholipids as a bioactive lipids, in addition to markers of oxidative stress and metabolic parameters, were analysed by GC chromatography. The food was well tolerated by all dogs, and the compliance to the diet was high throughout the study. After the treatment with fish-based food, blood glucose, total, and LDL cholesterol levels were significantly reduced, indicating positive biochemical profiles of dogs. Correlations of fatty acid phospholipid compositions between plasma and erythrocytes have shown that both plasma and erythrocytes could represent markers of omega-3 eicosapentaenoic and docosahexaenoic acid intake levels in dogs. Morover, fish-based food supplementation caused a significant reduction in lipid peroxidation markers. The enrichment of dogs’ diets with marine fish could improve oxidative status and improve roles and status of bioactive lipids, such as membrane phospholipids and fatty acids, as its components in plasma and erythrocytes in police dogs exposed to intensive exercise. MDPI 2022-08-08 /pmc/articles/PMC9405924/ /pubmed/36008986 http://dx.doi.org/10.3390/biom12081092 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ravić, Branko
Debeljak-Martacić, Jasmina
Pokimica, Biljana
Vidović, Nevena
Ranković, Slavica
Glibetić, Marija
Stepanović, Predrag
Popović, Tamara
The Effect of Fish Oil-Based Foods on Lipid and Oxidative Status Parameters in Police Dogs
title The Effect of Fish Oil-Based Foods on Lipid and Oxidative Status Parameters in Police Dogs
title_full The Effect of Fish Oil-Based Foods on Lipid and Oxidative Status Parameters in Police Dogs
title_fullStr The Effect of Fish Oil-Based Foods on Lipid and Oxidative Status Parameters in Police Dogs
title_full_unstemmed The Effect of Fish Oil-Based Foods on Lipid and Oxidative Status Parameters in Police Dogs
title_short The Effect of Fish Oil-Based Foods on Lipid and Oxidative Status Parameters in Police Dogs
title_sort effect of fish oil-based foods on lipid and oxidative status parameters in police dogs
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405924/
https://www.ncbi.nlm.nih.gov/pubmed/36008986
http://dx.doi.org/10.3390/biom12081092
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