Exploitation of High Tumour GSH Levels for Targeted siRNA Delivery in Rhabdomyosarcoma Cells

Metastatic alveolar rhabdomyosarcoma (aRMS) is an aggressive paediatric cancer with a poor prognosis. Downregulation of critical tumour genes using targeted siRNA remains an obstacle, but association with nanoparticles could help to deliver, protect, target, and enhance penetration. siRNA towards tw...

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Detalles Bibliográficos
Autores principales: Duan, Chengchen, Townley, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405954/
https://www.ncbi.nlm.nih.gov/pubmed/36009022
http://dx.doi.org/10.3390/biom12081129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405954/
https://www.ncbi.nlm.nih.gov/pubmed/36009022
http://dx.doi.org/10.3390/biom12081129

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