Plasmodium falciparum Nicotinamidase as A Novel Antimalarial Target

Inhibition of Plasmodium falciparum nicotinamidase could represent a potential antimalarial since parasites require nicotinic acid to successfully recycle nicotinamide to NAD(+), and importantly, humans lack this biosynthetic enzyme. Recently, mechanism-based inhibitors of nicotinamidase have been d...

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Detalles Bibliográficos
Autores principales: Donu, Dickson, Sharma, Chiranjeev, Cen, Yana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405955/
https://www.ncbi.nlm.nih.gov/pubmed/36009002
http://dx.doi.org/10.3390/biom12081109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405955/
https://www.ncbi.nlm.nih.gov/pubmed/36009002
http://dx.doi.org/10.3390/biom12081109

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