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Tumor Antigenicity and a Pre-Existing Adaptive Immune Response in Advanced BRAF Mutant Colorectal Cancers

SIMPLE SUMMARY: BRAF mutant metastatic CRCs (BRAF-mCRCs) are considered a unique clinical entity characterized by a dismal prognosis and that do not respond efficiently to both standard chemotherapy and to orally selective inhibitors of BRAF(V600E). In this study, the gene expression profiles of 89...

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Detalles Bibliográficos
Autores principales: Bolzacchini, Elena, Libera, Laura, Church, Sarah E., Sahnane, Nora, Bombelli, Raffaella, Digiacomo, Nunzio, Giordano, Monica, Petracco, Guido, Sessa, Fausto, Capella, Carlo, Furlan, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9405961/
https://www.ncbi.nlm.nih.gov/pubmed/36010943
http://dx.doi.org/10.3390/cancers14163951