Cargando…

The Role of Rab Proteins in Parkinson’s Disease Synaptopathy

In patients affected by Parkinson’s disease (PD), the most common neurodegenerative movement disorder, the brain is characterized by the loss of dopaminergic neurons in the nigrostriatal system, leading to dyshomeostasis of the basal ganglia network activity that is linked to motility dysfunction. P...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bellucci, Arianna, Longhena, Francesca, Spillantini, Maria Grazia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406004/ https://www.ncbi.nlm.nih.gov/pubmed/36009486 http://dx.doi.org/10.3390/biomedicines10081941

Ejemplares similares

The Contribution of α-Synuclein Spreading to Parkinson's Disease Synaptopathy
por: Longhena, Francesca, et al.
Publicado: (2017)

Living in Promiscuity: The Multiple Partners of Alpha-Synuclein at the Synapse in Physiology and Pathology
por: Longhena, Francesca, et al.
Publicado: (2019)

Alpha synuclein post translational modifications: potential targets for Parkinson’s disease therapy?
por: Brembati, Viviana, et al.
Publicado: (2023)

Centrality of Early Synaptopathy in Parkinson’s Disease
por: Imbriani, Paola, et al.
Publicado: (2018)

Mitochondrial Dysfunction and α-Synuclein Synaptic Pathology in Parkinson's Disease: Who's on First?
por: Zaltieri, Michela, et al.
Publicado: (2015)

Changes in α-Synuclein Posttranslational Modifications in an AAV-Based Mouse Model of Parkinson’s Disease
por: Brembati, Viviana, et al.
Publicado: (2023)

Dopamine Transporter/α-Synuclein Complexes Are Altered in the Post Mortem Caudate Putamen of Parkinson’s Disease: An In Situ Proximity Ligation Assay Study
por: Longhena, Francesca, et al.
Publicado: (2018)

Alpha-Synuclein as a Prominent Actor in the Inflammatory Synaptopathy of Parkinson’s Disease
por: Cardinale, Antonella, et al.
Publicado: (2021)

Mechanisms of α-Synuclein Induced Synaptopathy in Parkinson's Disease
por: Bridi, Jessika C., et al.
Publicado: (2018)

Synapsin III gene silencing redeems alpha-synuclein transgenic mice from Parkinson's disease-like phenotype
por: Faustini, Gaia, et al.
Publicado: (2022)

Study of alpha-synuclein fibrillation: state of the art and expectations
por: Longhena, Francesca, et al.
Publicado: (2019)

Linking α-synuclein-induced synaptopathy and neural network dysfunction in early Parkinson’s disease
por: Kulkarni, Aishwarya S, et al.
Publicado: (2022)

Nuclear Factor-κB Dysregulation and α-Synuclein Pathology: Critical Interplay in the Pathogenesis of Parkinson’s Disease
por: Bellucci, Arianna, et al.
Publicado: (2020)

Amyotrophic lateral sclerosis as a synaptopathy
por: Fogarty, Matthew J.
Publicado: (2019)

NF-κB/c-Rel deficiency causes Parkinson’s disease-like prodromal symptoms and progressive pathology in mice
por: Parrella, Edoardo, et al.
Publicado: (2019)

Early Dyskinesias in Parkinson’s Disease Patients With Parkin Mutation: A Primary Corticostriatal Synaptopathy?
por: Sassone, Jenny, et al.
Publicado: (2019)

Molecular and Cellular Mechanisms of Synaptopathies
por: Ardiles, Alvaro O., et al.
Publicado: (2017)

Synaptopathy, circuitopathy and the computational biology of Huntington’s disease
por: Hannan, Anthony J.
Publicado: (2018)

Advances in the Pathogenesis of Auto-antibody-Induced Cerebellar Synaptopathies
por: Mitoma, Hiroshi, et al.
Publicado: (2022)

Editorial: Synaptopathies: from bench to bedside
por: Bramham, Clive R., et al.
Publicado: (2023)

Cochlear Synaptopathy and Noise-Induced Hidden Hearing Loss
por: Shi, Lijuan, et al.
Publicado: (2016)

Correction: Redistribution of DAT/α-Synuclein Complexes Visualized by “In Situ” Proximity Ligation Assay in Transgenic Mice Modelling Early Parkinson's Disease
por: Bellucci, Arianna, et al.
Publicado: (2012)

Blast-induced cochlear synaptopathy in chinchillas
por: Hickman, T. T., et al.
Publicado: (2018)

Ultrastructure of noise-induced cochlear synaptopathy
por: Moverman, Daniel J., et al.
Publicado: (2023)

Alpha-Synuclein in the Regulation of Brain Endothelial and Perivascular Cells: Gaps and Future Perspectives
por: Bogale, Tizibt Ashine, et al.
Publicado: (2021)

The Role of Rab Proteins in Mitophagy: Insights into Neurodegenerative Diseases
por: Shafique, Adeena, et al.
Publicado: (2023)

Methylphenidate Analogues as a New Class of Potential Disease-Modifying Agents for Parkinson’s Disease: Evidence from Cell Models and Alpha-Synuclein Transgenic Mice
por: Casiraghi, Andrea, et al.
Publicado: (2022)

Auditory synaptopathy, auditory neuropathy, and cochlear implantation
por: Shearer, Aiden Eliot, et al.
Publicado: (2019)

Transmission Disrupted: Modeling Auditory Synaptopathy in Zebrafish
por: Kindt, Katie S., et al.
Publicado: (2018)

The atypical Rab GTPase associated with Parkinson’s disease, Rab29, is localized to membranes
por: Nagai-Ito, Yuki, et al.
Publicado: (2022)

An Update on the Interplay between LRRK2, Rab GTPases and Parkinson’s Disease
por: Komori, Tadayuki, et al.
Publicado: (2023)

The Communication Between the Immune and Nervous Systems: The Role of IL-1β in Synaptopathies
por: Pozzi, Davide, et al.
Publicado: (2018)

Impaired intracellular trafficking defines early Parkinson's disease
por: Hunn, Benjamin H.M., et al.
Publicado: (2015)

Alzheimer’s disease as a synaptopathy: Evidence for dysfunction of synapses during disease progression
por: Meftah, Soraya, et al.
Publicado: (2023)

Binaural Processing Deficits Due to Synaptopathy and Myelin Defects
por: Budak, Maral, et al.
Publicado: (2022)

Categorization of tinnitus listeners with a focus on cochlear synaptopathy
por: Casolani, Chiara, et al.
Publicado: (2022)

Reliability and interrelations of seven proxy measures of cochlear synaptopathy
por: Guest, Hannah, et al.
Publicado: (2019)

Effects of age on electrophysiological measures of cochlear synaptopathy in humans
por: Carcagno, Samuele, et al.
Publicado: (2020)

Could Perinatal Asphyxia Induce a Synaptopathy? New Highlights from an Experimental Model
por: Herrera, María Inés, et al.
Publicado: (2017)

Rab GTPases in Parkinson's disease: a primer
por: Lara Ordóñez, Antonio Jesús, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_b05gpphkobk8kqal4bja3f9h66