TERT and TET2 Genetic Variants Affect Leukocyte Telomere Length and Clinical Outcome in Coronary Artery Disease Patients—A Possible Link to Clonal Hematopoiesis

Inherited and acquired mutations in hematopoietic stem cells can cause clonal expansion with increased risk of cardiovascular disease (CVD), a condition known for the clonal hematopoiesis of indeterminate potential (CHIP). Inherited genetic variants in two CHIP-associated genome loci, the telomerase...

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Detalles Bibliográficos
Autores principales: Opstad, Trine B., Solheim, Svein, Pettersen, Alf-Åge R., Kalstad, Are A., Arnesen, Harald, Seljeflot, Ingebjørg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406025/
https://www.ncbi.nlm.nih.gov/pubmed/36009574
http://dx.doi.org/10.3390/biomedicines10082027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406025/
https://www.ncbi.nlm.nih.gov/pubmed/36009574
http://dx.doi.org/10.3390/biomedicines10082027

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