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Hot-Spot-Specific Probe (HSSP) for Rapid and Accurate Detection of KRAS Mutations in Colorectal Cancer

Detection of oncogene mutations has significance for early diagnosis, customized treatment, treatment progression, and drug resistance monitoring. Here, we introduce a rapid, sensitive, and specific mutation detection assay based on the hot-spot-specific probe (HSSP), with improved clinical utility...

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Detalles Bibliográficos
Autores principales: Lee, Hyo Joo, Koo, Bonhan, Jang, Yoon Ok, Liu, Huifang, Dao, Thuy Nguyen Thi, Lim, Seok-Byung, Shin, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406089/
https://www.ncbi.nlm.nih.gov/pubmed/36004993
http://dx.doi.org/10.3390/bios12080597