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Temporal Heterogeneity of HER2 Expression and Spatial Heterogeneity of (18)F-FDG Uptake Predicts Treatment Outcome of Pyrotinib in Patients with HER2-Positive Metastatic Breast Cancer

SIMPLE SUMMARY: Tumor heterogeneity plays an important role in malignant behaviors and treatment responses. This study aimed to evaluate the temporal and spatial heterogeneity in clinical practice and investigate its impact on the treatment outcome of pyrotinib in patients with HER2-positive metasta...

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Detalles Bibliográficos
Autores principales:	Gong, Chengcheng, Liu, Cheng, Tao, Zhonghua, Zhang, Jian, Wang, Leiping, Cao, Jun, Zhao, Yannan, Xie, Yizhao, Hu, Xichun, Yang, Zhongyi, Wang, Biyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406192/ https://www.ncbi.nlm.nih.gov/pubmed/36010967 http://dx.doi.org/10.3390/cancers14163973

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