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(3α,5α)3-Hydroxypregnan-20-one (3α,5α-THP) Regulation of the HPA Axis in the Context of Different Stressors and Sex

Corticotropin-releasing factor (CRF) regulates the stress response in the hypothalamus and modulates neurotransmission across the brain through CRF receptors. Acute stress increases hypothalamic CRF and the GABAergic neurosteroid (3α,5α)3-hydroxypregnan-20-one (3α,5α-THP). We previously showed that...

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Detalles Bibliográficos
Autores principales: Boero, Giorgia, Tyler, Ryan E., O’Buckley, Todd K., Balan, Irina, Besheer, Joyce, Morrow, A. Leslie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406198/
https://www.ncbi.nlm.nih.gov/pubmed/36009028
http://dx.doi.org/10.3390/biom12081134