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The Management of Asymptomatic Congenital Pulmonary Airway Malformation: Results of a European Delphi Survey

Consensus on the optimal management of asymptomatic congenital pulmonary airway malformation (CPAM) is lacking, and comparison between studies remains difficult due to a large variety in outcome measures. We aimed to define a core outcome set (COS) for pediatric patients with an asymptomatic CPAM. A...

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Autores principales: Kersten, Casper M., Hermelijn, Sergei M., Mullassery, Dhanya, Muthialu, Nagarajan, Cobanoglu, Nazan, Gartner, Silvia, Bagolan, Pietro, Mesas Burgos, Carmen, Sgrò, Alberto, Heyman, Stijn, Till, Holger, Suominen, Janne, Schurink, Maarten, Desender, Liesbeth, Losty, Paul, Steyaert, Henri, Terheggen-Lagro, Suzanne, Metzelder, Martin, Bonnard, Arnaud, Sfeir, Rony, Singh, Michael, Yardley, Iain, Rikkers-Mutsaerts, Noor R. V. M., van der Ent, Cornelis K., Qvist, Niels, Cox, Des W., Peters, Robert, Bannier, Michiel A. G. E., Wessel, Lucas, Proesmans, Marijke, Stanton, Michael, Hannon, Edward, Zampoli, Marco, Morini, Francesco, Tiddens, Harm A. W. M., Wijnen, René M. H., Schnater, Johannes M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406306/
https://www.ncbi.nlm.nih.gov/pubmed/36010044
http://dx.doi.org/10.3390/children9081153
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author Kersten, Casper M.
Hermelijn, Sergei M.
Mullassery, Dhanya
Muthialu, Nagarajan
Cobanoglu, Nazan
Gartner, Silvia
Bagolan, Pietro
Mesas Burgos, Carmen
Sgrò, Alberto
Heyman, Stijn
Till, Holger
Suominen, Janne
Schurink, Maarten
Desender, Liesbeth
Losty, Paul
Steyaert, Henri
Terheggen-Lagro, Suzanne
Metzelder, Martin
Bonnard, Arnaud
Sfeir, Rony
Singh, Michael
Yardley, Iain
Rikkers-Mutsaerts, Noor R. V. M.
van der Ent, Cornelis K.
Qvist, Niels
Cox, Des W.
Peters, Robert
Bannier, Michiel A. G. E.
Wessel, Lucas
Proesmans, Marijke
Stanton, Michael
Hannon, Edward
Zampoli, Marco
Morini, Francesco
Tiddens, Harm A. W. M.
Wijnen, René M. H.
Schnater, Johannes M.
author_facet Kersten, Casper M.
Hermelijn, Sergei M.
Mullassery, Dhanya
Muthialu, Nagarajan
Cobanoglu, Nazan
Gartner, Silvia
Bagolan, Pietro
Mesas Burgos, Carmen
Sgrò, Alberto
Heyman, Stijn
Till, Holger
Suominen, Janne
Schurink, Maarten
Desender, Liesbeth
Losty, Paul
Steyaert, Henri
Terheggen-Lagro, Suzanne
Metzelder, Martin
Bonnard, Arnaud
Sfeir, Rony
Singh, Michael
Yardley, Iain
Rikkers-Mutsaerts, Noor R. V. M.
van der Ent, Cornelis K.
Qvist, Niels
Cox, Des W.
Peters, Robert
Bannier, Michiel A. G. E.
Wessel, Lucas
Proesmans, Marijke
Stanton, Michael
Hannon, Edward
Zampoli, Marco
Morini, Francesco
Tiddens, Harm A. W. M.
Wijnen, René M. H.
Schnater, Johannes M.
author_sort Kersten, Casper M.
collection PubMed
description Consensus on the optimal management of asymptomatic congenital pulmonary airway malformation (CPAM) is lacking, and comparison between studies remains difficult due to a large variety in outcome measures. We aimed to define a core outcome set (COS) for pediatric patients with an asymptomatic CPAM. An online, three-round Delphi survey was conducted in two stakeholder groups of specialized caregivers (surgeons and non-surgeons) in various European centers. Proposed outcome parameters were scored according to level of importance, and the final COS was established through consensus. A total of 55 participants (33 surgeons, 22 non-surgeons) from 28 centers in 13 European countries completed the three rounds and rated 43 outcome parameters. The final COS comprises seven outcome parameters: respiratory insufficiency, surgical complications, mass effect/mediastinal shift (at three time-points) and multifocal disease (at two time-points). The seven outcome parameters included in the final COS reflect the diversity in priorities among this large group of European participants. However, we recommend the incorporation of these outcome parameters in the design of future studies, as they describe measurable and validated outcomes as well as the accepted age at measurement.
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spelling pubmed-94063062022-08-26 The Management of Asymptomatic Congenital Pulmonary Airway Malformation: Results of a European Delphi Survey Kersten, Casper M. Hermelijn, Sergei M. Mullassery, Dhanya Muthialu, Nagarajan Cobanoglu, Nazan Gartner, Silvia Bagolan, Pietro Mesas Burgos, Carmen Sgrò, Alberto Heyman, Stijn Till, Holger Suominen, Janne Schurink, Maarten Desender, Liesbeth Losty, Paul Steyaert, Henri Terheggen-Lagro, Suzanne Metzelder, Martin Bonnard, Arnaud Sfeir, Rony Singh, Michael Yardley, Iain Rikkers-Mutsaerts, Noor R. V. M. van der Ent, Cornelis K. Qvist, Niels Cox, Des W. Peters, Robert Bannier, Michiel A. G. E. Wessel, Lucas Proesmans, Marijke Stanton, Michael Hannon, Edward Zampoli, Marco Morini, Francesco Tiddens, Harm A. W. M. Wijnen, René M. H. Schnater, Johannes M. Children (Basel) Article Consensus on the optimal management of asymptomatic congenital pulmonary airway malformation (CPAM) is lacking, and comparison between studies remains difficult due to a large variety in outcome measures. We aimed to define a core outcome set (COS) for pediatric patients with an asymptomatic CPAM. An online, three-round Delphi survey was conducted in two stakeholder groups of specialized caregivers (surgeons and non-surgeons) in various European centers. Proposed outcome parameters were scored according to level of importance, and the final COS was established through consensus. A total of 55 participants (33 surgeons, 22 non-surgeons) from 28 centers in 13 European countries completed the three rounds and rated 43 outcome parameters. The final COS comprises seven outcome parameters: respiratory insufficiency, surgical complications, mass effect/mediastinal shift (at three time-points) and multifocal disease (at two time-points). The seven outcome parameters included in the final COS reflect the diversity in priorities among this large group of European participants. However, we recommend the incorporation of these outcome parameters in the design of future studies, as they describe measurable and validated outcomes as well as the accepted age at measurement. MDPI 2022-07-30 /pmc/articles/PMC9406306/ /pubmed/36010044 http://dx.doi.org/10.3390/children9081153 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kersten, Casper M.
Hermelijn, Sergei M.
Mullassery, Dhanya
Muthialu, Nagarajan
Cobanoglu, Nazan
Gartner, Silvia
Bagolan, Pietro
Mesas Burgos, Carmen
Sgrò, Alberto
Heyman, Stijn
Till, Holger
Suominen, Janne
Schurink, Maarten
Desender, Liesbeth
Losty, Paul
Steyaert, Henri
Terheggen-Lagro, Suzanne
Metzelder, Martin
Bonnard, Arnaud
Sfeir, Rony
Singh, Michael
Yardley, Iain
Rikkers-Mutsaerts, Noor R. V. M.
van der Ent, Cornelis K.
Qvist, Niels
Cox, Des W.
Peters, Robert
Bannier, Michiel A. G. E.
Wessel, Lucas
Proesmans, Marijke
Stanton, Michael
Hannon, Edward
Zampoli, Marco
Morini, Francesco
Tiddens, Harm A. W. M.
Wijnen, René M. H.
Schnater, Johannes M.
The Management of Asymptomatic Congenital Pulmonary Airway Malformation: Results of a European Delphi Survey
title The Management of Asymptomatic Congenital Pulmonary Airway Malformation: Results of a European Delphi Survey
title_full The Management of Asymptomatic Congenital Pulmonary Airway Malformation: Results of a European Delphi Survey
title_fullStr The Management of Asymptomatic Congenital Pulmonary Airway Malformation: Results of a European Delphi Survey
title_full_unstemmed The Management of Asymptomatic Congenital Pulmonary Airway Malformation: Results of a European Delphi Survey
title_short The Management of Asymptomatic Congenital Pulmonary Airway Malformation: Results of a European Delphi Survey
title_sort management of asymptomatic congenital pulmonary airway malformation: results of a european delphi survey
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406306/
https://www.ncbi.nlm.nih.gov/pubmed/36010044
http://dx.doi.org/10.3390/children9081153
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