Cargando…
Methyltransferase Setdb1 Promotes Osteoblast Proliferation by Epigenetically Silencing Macrod2 with the Assistance of Atf7ip
Bone loss caused by mechanical unloading is a threat to prolonged space flight and human health. Epigenetic modifications play a crucial role in varied biological processes, but the mechanism of histone modification on unloading-induced bone loss has rarely been studied. Here, we discovered for the...
Autores principales: | Zhang, Lijun, Xu, Liqun, Zhang, Xiaoyan, Wang, Ke, Tan, Yingjun, Li, Gaozhi, Wang, Yixuan, Xue, Tong, Sun, Quan, Cao, Xinsheng, Zhang, Ge, Hu, Zebing, Zhang, Shu, Shi, Fei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406310/ https://www.ncbi.nlm.nih.gov/pubmed/36010655 http://dx.doi.org/10.3390/cells11162580 |
Ejemplares similares
-
Circulating Exosomes from Mice with LPS-Induced Bone Loss Inhibit Osteoblast Differentiation
por: Wang, Yixuan, et al.
Publicado: (2022) -
ATF7IP-Mediated Stabilization of the Histone Methyltransferase SETDB1 Is Essential for Heterochromatin Formation by the HUSH Complex
por: Timms, Richard T., et al.
Publicado: (2016) -
Targeted overexpression of the long noncoding RNA ODSM can regulate osteoblast function in vitro and in vivo
por: Wang, Yixuan, et al.
Publicado: (2020) -
The fibronectin type-III (FNIII) domain of ATF7IP contributes to efficient transcriptional silencing mediated by the SETDB1 complex
por: Tsusaka, Takeshi, et al.
Publicado: (2020) -
MicroRNA-139-3p regulates osteoblast differentiation and apoptosis by targeting ELK1 and interacting with long noncoding RNA ODSM
por: Wang, Yixuan, et al.
Publicado: (2018)