Cargando…

Craniofacial Growth at Age 6–11 Years after One-Stage Cleft Lip and Palate Repair: A Retrospective Comparative Study with Historical Controls

Background: Primary alveolar bone grafting inhibits craniofacial growth. However, its effect on craniofacial growth in one-stage cleft lip and palate protocols is unknown. This study investigated whether primary alveolar bone grafting performed during one-stage unilateral cleft lip and palate repair...

Descripción completa

Detalles Bibliográficos
Autores principales: Benitez, Benito K., Weibel, Seraina K., Halbeisen, Florian S., Lill, Yoriko, Nalabothu, Prasad, Tache, Ana, Mueller, Andreas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406322/
https://www.ncbi.nlm.nih.gov/pubmed/36010118
http://dx.doi.org/10.3390/children9081228
_version_ 1784774092332728320
author Benitez, Benito K.
Weibel, Seraina K.
Halbeisen, Florian S.
Lill, Yoriko
Nalabothu, Prasad
Tache, Ana
Mueller, Andreas A.
author_facet Benitez, Benito K.
Weibel, Seraina K.
Halbeisen, Florian S.
Lill, Yoriko
Nalabothu, Prasad
Tache, Ana
Mueller, Andreas A.
author_sort Benitez, Benito K.
collection PubMed
description Background: Primary alveolar bone grafting inhibits craniofacial growth. However, its effect on craniofacial growth in one-stage cleft lip and palate protocols is unknown. This study investigated whether primary alveolar bone grafting performed during one-stage unilateral cleft lip and palate repair negatively affects growth up to 6–11 years old. Methods: The craniofacial growth, dental arch relationship and palatal morphology at 6–11 years old in children with unilateral cleft lip and palate were compared retrospectively. Two cohorts after a one-stage protocol without (Group A) and with (Group B) primary bone grafting at the same center were compared. Further, cephalometric measurements for growth were compared with an external cohort of a one-stage protocol and a heathy control. Results: Group A comprised 16 patients assessed at 6.8 years (SD 0.83), and Group B comprised 15 patients assessed at 9 years (SD 2.0). Cephalometric measurements indicated similar sagittal maxillary growth deficits and a significant deviation in maxillary inclination in both groups compared to the healthy group. Moderate to severe changes in palatal morphology were observed in 70% of the members in both groups. Conclusion: Omitting primary alveolar bone grafting under the one-stage protocol with two-flap palatoplasty studied did not improve growth at 6–11 years. The results implicate two-flap palatoplasty with secondary healing as having greater adverse effects on growth than primary alveolar bone grafting. Dental and palatal morphology was considerably compromised regardless of primary alveolar bone grafting.
format Online
Article
Text
id pubmed-9406322
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-94063222022-08-26 Craniofacial Growth at Age 6–11 Years after One-Stage Cleft Lip and Palate Repair: A Retrospective Comparative Study with Historical Controls Benitez, Benito K. Weibel, Seraina K. Halbeisen, Florian S. Lill, Yoriko Nalabothu, Prasad Tache, Ana Mueller, Andreas A. Children (Basel) Article Background: Primary alveolar bone grafting inhibits craniofacial growth. However, its effect on craniofacial growth in one-stage cleft lip and palate protocols is unknown. This study investigated whether primary alveolar bone grafting performed during one-stage unilateral cleft lip and palate repair negatively affects growth up to 6–11 years old. Methods: The craniofacial growth, dental arch relationship and palatal morphology at 6–11 years old in children with unilateral cleft lip and palate were compared retrospectively. Two cohorts after a one-stage protocol without (Group A) and with (Group B) primary bone grafting at the same center were compared. Further, cephalometric measurements for growth were compared with an external cohort of a one-stage protocol and a heathy control. Results: Group A comprised 16 patients assessed at 6.8 years (SD 0.83), and Group B comprised 15 patients assessed at 9 years (SD 2.0). Cephalometric measurements indicated similar sagittal maxillary growth deficits and a significant deviation in maxillary inclination in both groups compared to the healthy group. Moderate to severe changes in palatal morphology were observed in 70% of the members in both groups. Conclusion: Omitting primary alveolar bone grafting under the one-stage protocol with two-flap palatoplasty studied did not improve growth at 6–11 years. The results implicate two-flap palatoplasty with secondary healing as having greater adverse effects on growth than primary alveolar bone grafting. Dental and palatal morphology was considerably compromised regardless of primary alveolar bone grafting. MDPI 2022-08-13 /pmc/articles/PMC9406322/ /pubmed/36010118 http://dx.doi.org/10.3390/children9081228 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Benitez, Benito K.
Weibel, Seraina K.
Halbeisen, Florian S.
Lill, Yoriko
Nalabothu, Prasad
Tache, Ana
Mueller, Andreas A.
Craniofacial Growth at Age 6–11 Years after One-Stage Cleft Lip and Palate Repair: A Retrospective Comparative Study with Historical Controls
title Craniofacial Growth at Age 6–11 Years after One-Stage Cleft Lip and Palate Repair: A Retrospective Comparative Study with Historical Controls
title_full Craniofacial Growth at Age 6–11 Years after One-Stage Cleft Lip and Palate Repair: A Retrospective Comparative Study with Historical Controls
title_fullStr Craniofacial Growth at Age 6–11 Years after One-Stage Cleft Lip and Palate Repair: A Retrospective Comparative Study with Historical Controls
title_full_unstemmed Craniofacial Growth at Age 6–11 Years after One-Stage Cleft Lip and Palate Repair: A Retrospective Comparative Study with Historical Controls
title_short Craniofacial Growth at Age 6–11 Years after One-Stage Cleft Lip and Palate Repair: A Retrospective Comparative Study with Historical Controls
title_sort craniofacial growth at age 6–11 years after one-stage cleft lip and palate repair: a retrospective comparative study with historical controls
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406322/
https://www.ncbi.nlm.nih.gov/pubmed/36010118
http://dx.doi.org/10.3390/children9081228
work_keys_str_mv AT benitezbenitok craniofacialgrowthatage611yearsafteronestagecleftlipandpalaterepairaretrospectivecomparativestudywithhistoricalcontrols
AT weibelserainak craniofacialgrowthatage611yearsafteronestagecleftlipandpalaterepairaretrospectivecomparativestudywithhistoricalcontrols
AT halbeisenflorians craniofacialgrowthatage611yearsafteronestagecleftlipandpalaterepairaretrospectivecomparativestudywithhistoricalcontrols
AT lillyoriko craniofacialgrowthatage611yearsafteronestagecleftlipandpalaterepairaretrospectivecomparativestudywithhistoricalcontrols
AT nalabothuprasad craniofacialgrowthatage611yearsafteronestagecleftlipandpalaterepairaretrospectivecomparativestudywithhistoricalcontrols
AT tacheana craniofacialgrowthatage611yearsafteronestagecleftlipandpalaterepairaretrospectivecomparativestudywithhistoricalcontrols
AT muellerandreasa craniofacialgrowthatage611yearsafteronestagecleftlipandpalaterepairaretrospectivecomparativestudywithhistoricalcontrols