Early Dietary Exposures Epigenetically Program Mammary Cancer Susceptibility through Igf1-Mediated Expansion of the Mammary Stem Cell Compartment

Diet is a critical environmental factor affecting breast cancer risk, and recent evidence shows that dietary exposures during early development can affect lifetime mammary cancer susceptibility. To elucidate the underlying mechanisms, we used our established crossover feeding mouse model, where expo...

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Detalles Bibliográficos
Autores principales: Zheng, Yuanning, Luo, Linjie, Lambertz, Isabel U., Conti, Claudio J., Fuchs-Young, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406400/
https://www.ncbi.nlm.nih.gov/pubmed/36010633
http://dx.doi.org/10.3390/cells11162558

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