Integration of Human Protein Sequence and Protein-Protein Interaction Data by Graph Autoencoder to Identify Novel Protein-Abnormal Phenotype Associations

Understanding gene functions and their associated abnormal phenotypes is crucial in the prevention, diagnosis and treatment against diseases. The Human Phenotype Ontology (HPO) is a standardized vocabulary for describing the phenotype abnormalities associated with human diseases. However, the curren...

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Detalles Bibliográficos
Autores principales: Liu, Yuan, He, Ruirui, Qu, Yingjie, Zhu, Yuan, Li, Dianke, Ling, Xinping, Xia, Simin, Li, Zhenqiu, Li, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406402/
https://www.ncbi.nlm.nih.gov/pubmed/36010562
http://dx.doi.org/10.3390/cells11162485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9406402/
https://www.ncbi.nlm.nih.gov/pubmed/36010562
http://dx.doi.org/10.3390/cells11162485

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